Flavonoids that bind DNA block a mutagen’s chemical fingerprints in lab tests
Licoricidin and isoliquiritigenin bind directly to DNA and reduce MNU-induced methylated adducts in bacterial and cell-free systems, though DNA binding ...
Tag: Genes and Environment
Research report: Application of chimeric mice with human hepatocytes for the evaluation of metabolically activated genotoxic substances
A repeated-dose liver micronucleus assay in chimeric mice with human hepatocytes detected genotoxicity of DEN and NDMA, compounds that require ...
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