Banana DMR6 induction tracks Fusarium wilt progression in Prata-Ana
A controlled infection study links late induction of the banana susceptibility gene MusaDMR6 to Fusarium wilt progression in the commercially ...
Tag: gene
Regulatory Evolution Offers Clues to Horn Diversification in Beetles
A comparative study in two beetle species links evolving regulatory DNA and condition-specific chromatin changes to horn diversification, with functional ...
AAV gene replacement restores Parkin pathway activity in preclinical tests
An AAV carrying functional human PRKN restored mitochondrial-pathway signaling in Parkin-deficient cells and patient fibroblasts, while rodent tests showed that ...
Gene architecture predicts isoform diversity across four genomes
Longer introns, shorter exons and more complex gene organization were consistently associated with higher transcript-isoform diversity in humans, mice, flies ...
Small case-control study finds possible CCR2–sarcoidosis association
A targeted-sequencing case-control study of 50 people found that one CCR2 variant was more frequent in the sarcoidosis group, suggesting ...
The landscape of gene loss and missense variation across the mammalian tree informs on gene essentiality
A comparative analysis of 462 mammals produced two evolutionary constraint measures associated with human gene-importance metrics while identifying short genes ...
Karyotype and COI sequence of Chironomus heteropilicornis from Gydan Peninsula
Chromosome and COI analyses characterized a newly recorded Chironomus heteropilicornis population from Russia’s Gydan Peninsula and placed its barcode with ...
Research report: Karyotype characteristics and gene COI sequences of Chironomus bonus Shilova et Dzhvarsheishvili, 1974 ( Diptera , Chironomidae ) from the South Caucasus (Republic of Georgia, Paravani river)
A Georgian study of Chironomus bonus linked its additional B chromosome and first mitochondrial COI sequences to a closely related ...
Gene Behind Rare Metabolic Disorder Also Drives Inherited Blindness, Study Finds
Retinitis pigmentosa has long been understood as a genetically heterogeneous condition, meaning that mutations in many different genes can produce ...
New AI Tool Fuses Fragmented Biology Into a Reusable Gene Network
Genomics has a stubborn arithmetic problem. In most modern association studies, the number of candidate genes runs into the tens ...
Mechanosensitive Gene Signature Predicts Colorectal Cancer Liver Metastasis Risk
Colorectal cancer is one of the most common and deadliest malignancies worldwide, and its spread to the liver is the ...
Mini-Dystrophin Levels Track With Muscle Strength in Rat Gene Therapy Study
Duchenne muscular dystrophy has long presented gene therapists with a deceptively simple question: how much dystrophin does a patient need, ...
AAV Vector Manufacturing Advances Hold the Key to Accessible Gene Therapy
Adeno-associated virus (AAV) vectors have become the delivery vehicle of choice for modern gene therapy, carrying therapeutic genes into cells ...
Watermelon PR1 Genes Reveal Ethylene-Linked Defense Against CGMMV
Watermelon, one of the most economically important fruit crops in the world, is under persistent threat from cucumber green mottle ...
HOXA5 gene silencing by DNA methylation drives oral cancer development, study reveals
Scientists have uncovered a critical epigenetic mechanism behind oral cancer, showing that a gene called HOXA5 is switched off by ...
From cooperation to collapse: the diet-microbiota-host gene triad in disease and aging
A new review in Frontiers in Microbiomes argues that aging and disease reflect the collapse of an ancient symbiotic network ...
Rice Seed-Size Genes Point the Way to Bigger Groundnut Kernels
A comparative genomics study in groundnut shows that rice seed-size genes GW5, GW7, GS3 and GS2 are expressed differently in ...
HNRNPH2-R114W remodels RNA splicing and neurodevelopmental gene programs in isogenic cerebral organoids
A single letter change in a protein that shepherds RNA through the splicing machinery may be enough to rewire thousands ...
Ancient Gene Family Revealed as Master Switch in Hardy Rubber Tree’s Growth and Stress Survival
Researchers have systematically identified the complete KNOX gene family in the hardy rubber tree Eucommia ulmoides, revealing how these ancient ...
Spatiotemporal AI-based modeling of gene regulation and variant effects in the developing human brain using Seal
The developing human brain presents one of the most formidable modeling challenges in modern biology because its regulatory landscape is ...
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