Genes May Shape How Air Pollution Touches Thyroid Hormone Levels
A genome-wide interaction study in Korean adults identifies suggestive genetic loci, including MSRA, PCAT1, and GCOM1, that may modify the ...
Tag: Gene-environment interaction
Genes, Environment and Multi-Omics Maps Reshape How IPF Is Understood and Predicted
A wide-ranging review links genetic variation, multi-omics mechanisms and environmental exposures in idiopathic pulmonary fibrosis, proposing a multi-gene risk score ...
Archived DNA from German uranium miners confirms gene variants that shape radon-linked lung cancer risk
A study of archived DNA from 526 former WISMUT uranium miners with lung cancer found that mining radon exposure significantly ...
Genes and gut microbes shape who tolerates GLP-1 drugs, but never together
Nausea, vomiting, diarrhea and constipation are the price many people pay for the remarkable weight loss and blood sugar control ...
fastGxE maps gene–environment interactions across UK Biobank traits
fastGxE found 25 candidate gene–environment interaction loci across 99 UK Biobank traits, including 16 loci not previously associated with these ...
Long-term air pollution exposure linked with bladder cancer risk in prospective UK Biobank analysis
A prospective UK Biobank analysis of 469,105 participants linked long-term exposure to four air pollutants with increased bladder cancer risk, ...
Vitamin D Levels and Receptor Gene Variants Combine to Drive Kidney Stone Risk
A new case-control study from a genetically homogeneous population in India reveals that elevated serum vitamin D and specific vitamin ...
Poor Diet May Amplify Genetic Cholesterol Risk in Asian Indian Adults, Chennai Study Finds
A study of 1,020 adults in Chennai found that poor diet quality significantly amplifies the effect of genetic predisposition to ...
Scientists Rethink How Metal Mixtures in the Womb Shape Baby Birth Size
A methodological exchange in Pediatric Research highlights how Bayesian mixture models and genetic susceptibility are reshaping the study of prenatal ...
Gene Variants That Detoxify Tobacco Carcinogens Reshape Oral Cancer Risk
A critical review of 21 studies finds that inherited variants in carcinogen-metabolizing enzymes, especially GSTM1 and GSTT1 null genotypes, modulate ...
Heart Disease Genetics: Little-Known Chaperone Hero11 Emerges as Coronary Risk Gene
Genetic variants in the heat-resistant obscure chaperone protein Hero11, encoded by C19orf53, are associated with coronary artery disease risk and ...
Genetic, Age, and Alcohol Factors Identify Hypertension Risk
Recent investigations into the genetic underpinnings of hypertension have revealed intricate relationships between genetic variations, lifestyle factors, and clinical outcomes. ...
