Tag: Gasdermin D

In a lithium-pilocarpine rat model of status epilepticus, hippocampal GSDMD knockdown reduced pyroptosis and ferroptosis markers, improved neuronal survival, and ...

A new review distinguishes a myeloid gasdermin D inflammatory relay from photoreceptor-intrinsic gasdermin E lysis in retinal degeneration and grades ...

Researchers at Sun Yat-sen University show that blocking the cGAS-STING pathway and the NLRP3 inflammasome reduces inflammatory cell death and ...

New research in PLOS Pathogens reveals that exercise drives a protective metabolite pathway that pushes the NLRP3 inflammasome into a ...

New research shows that gasdermin D pores formed during pyroptosis can admit selectively designed caspase inhibitors, allowing the inflammatory cell ...

A new mouse study shows that hyperactive NLRP3 inflammasome signaling within vascular smooth muscle cells drives inflammation, pyroptosis, lipid accumulation, ...

New research shows that salvianolic acid B, a polyphenol from red sage, protects human heart muscle cells from high-glucose injury ...

In recent years, the landscape of neurodegenerative diseases has undergone transformative changes, particularly in our understanding of frontotemporal dementia (FTD). ...

In a groundbreaking development that sheds new light on the pathogenesis of bronchopulmonary dysplasia (BPD), researchers have identified a pivotal ...