COMP-MUC1 Salt Bridge Drives Prostate Cancer Bone Metastasis via Ferroptosis Resistance
Researchers found that COMP interacts directly with MUC1 to confer ferroptosis resistance and drive prostate cancer bone metastasis.
Tag: Ferroptosis resistance
Patient-derived cells reveal metabolic and lysosomal defects in TFE3 neurodevelopmental disorder
Patient-derived fibroblasts with TFE3-associated neurodevelopmental disorder showed metabolic rigidity, dysfunctional lysosomes, impaired migration and an unstable extracellular-matrix interface.
Groundbreaking Discovery in Colorectal Cancer: Novel lncRNA ESSENCE Unveiled as Critical Driver of Tumor Growth
Colorectal cancer (CRC) continues to rank among the most common and lethal malignancies globally, presenting an ongoing challenge for clinicians ...
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