TGF-β signaling symposium reveals new paths from development to cancer therapy
Researchers meeting in Nanchang reported new mechanisms of TGF-β signaling in stem cell differentiation, cancer, fibrosis and immunity, alongside inhibitors ...
Tag: embryonic stem cells
Gingival fibroblast-derived iPSCs show broad methylation convergence with residual somatic patterns
A methylation comparison of human gingival fibroblasts, their derived iPSCs and an embryonic stem-cell reference found broad pluripotent-state convergence alongside ...
Scientists Map the Earliest Steps of Polycomb Gene Silencing in Human Embryos
A Nature Genetics study shows that the histone mark H2Aub laid down by PRC1 guides the reestablishment of Polycomb repression, ...
Super Elongation Complex Found to Switch On Genes That Transform Cell Identity
New research shows that the Super Elongation Complex drives both stem cell reprogramming and neural differentiation by releasing paused RNA ...
Mini Blood Vessels in a Miniature Plate: 96-Well Platform Streamlines Organoid Production
Researchers in China have adapted blood vessel organoid production to a 96-well ultra-low-attachment plate, enabling independent, cost-effective, and higher-throughput vascular ...
3D Printing Human Embryonic Stem Cells
A team of researchers from Scotland has used a novel 3D printing technique to arrange human embryonic stem cells (hESCs) ...
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