Malaria Parasite RNA Helicase PfDDX1 Emerges as a Regulator of Blood-Stage Development
A new study shows that the conserved DEAD-box RNA helicase PfDDX1 modulates the pace of intraerythrocytic development and gene expression ...
Tag: CRISPR-Cas9
Silkworm Study Reveals Ancient Receptor Mechanism Behind Insect Skin Patterns
Researchers show that the ligand-independent nuclear receptor BmERR uses its AF-2 domain to recruit the coactivator PPRC1 and control melanin-driven ...
A Smell Receptor in the Brain Drives Neurite Growth Through CREB Signaling
Scientists have shown that the olfactory receptor Olfr544, found near amyloid plaques in Alzheimer's model mice, drives neurite outgrowth in ...
CRISPR Milestone and Gene Therapy Redefine the Curative Landscape of Beta-Thalassemia
A new review charts how stem cell transplantation, lentiviral gene therapy, and CRISPR-based editing such as Casgevy are turning beta-thalassemia ...
Enzyme Tag-Team Lets Caterpillarpests Beat Plant Toxins and Expand Their Menu
A coordinated P450 and UGT33 detoxification cascade allows the generalist moth Helicoverpa armigera to tolerate furanocoumarin plant toxins, while its ...
Silencing HPV16 Oncogenes E5 and E6 Emerges as a Promising Route Against Cervical Cancer
A new review in Virology Journal examines how siRNA and CRISPR/Cas gene-silencing technologies could target the HPV16 oncoproteins E5 and ...
A Nodule Protein Mystery: Deleting a Highly Expressed Legume Gene Leaves Nitrogen Fixation Untouched
CRISPR-generated knockout mutants reveal that the highly expressed, symbiosome-localized nodulin NOD25 is dispensable for nitrogen-fixing symbiosis in Medicago truncatula, pointing ...
Cotton’s Fiber-Seed Trade-Off Cracked: GhRCD1-GhMYC3 Module Promises Premium Fiber and Vigorous Seeds Together
Chinese researchers have identified the GhRCD1-GhMYC3 protein module that governs cotton's long-standing trade-off between fiber quality and seed performance, offering ...
A Single DNA Letter Tweak Rewires a Cancer Gene’s Translation and Stress Response
A common inherited variant in the DDIT4 3′ UTR controls translation efficiency of the tumor-suppressing stress-response gene, reshaping mTOR signaling, ...
Compact tomato pangenome reveals genes steering fruit size and disease defense
A streamlined graph-based tomato pangenome built from cultivated and wild parents has uncovered a new fruit-weight gene and a regulator ...
Two New Genes That Shorten Rice Stems Could Help Breed Lodging-Proof Crops
A genome-wide association study of 429 rice accessions combined with CRISPR/Cas9 validation has identified two new genes, INL1 and INL2, ...
Female Mice Pay a Heavier Price: Sex Hormones Speed Retinal Degeneration
New research shows that female mice lacking the protein quality-control gene Herc3 suffer faster retinal thinning, greater inflammatory activation, and ...
Targeted Oncogene Editing Induces Tumor Remodelling and Immunity
Recent advancements in cancer research have illuminated the path toward innovative therapeutic strategies aimed at precision medicine. A pivotal study ...
CRISPR Screens Identify Genes Driving Neuronal Differentiation
In a groundbreaking study published in Nature Neuroscience, researchers have unveiled new insights into the genetic underpinnings of neurodevelopmental disorders ...
Transcription Factors Guide Leaf Margin Growth in Roses
In the realm of plant biology, the intricate mechanisms that govern the development of plant structures are of paramount interest. ...
Gene Editing Breakthroughs for Collagen Disorders Ahead
In a groundbreaking study published in Gene Therapy, researchers have illuminated the possibilities of gene editing for collagen disorders, highlighting ...
Progress in Collagen Disorder Research and Treatments
In recent years, the scientific community has made significant strides in the understanding and treatment of collagen disorders, a diverse ...
