Tag: combination therapy

A new review explains why BCG immunotherapy fails in some bladder cancer patients and outlines emerging combination strategies designed to ...

A new perspective argues that pairing non-invasive brain stimulation with pro-remyelinating drugs could target both oligodendrocyte differentiation and the hostile ...

A comprehensive Molecular Cancer review explains how antibody-drug conjugates deliver lethal payloads to tumors, why resistance emerges, and which next-generation ...

The Hairy Cell Leukemia Foundation and Blood Cancer United have announced six new research grants worth nearly $7 million to ...

A new cell study shows that C-phycocyanin can strip away Mcl-1-driven resistance and make the BH3-mimetic ABT-737 far more lethal ...

New research reveals that the immune checkpoint protein B7-H3 fuels triple-negative breast cancer from within by sustaining SP1-dependent HSPA8 chaperone ...

A two-center retrospective study found that adding TACE or HAIC to targeted-immunotherapy nearly doubled median overall survival in advanced hepatocellular ...

New research shows that inhibiting the FGFR signaling pathway reduces T cell exhaustion and repolarizes macrophages, significantly enhancing PD-1 blockade ...

A new quantitative systems pharmacology model spanning all three classes of BRAF-mutant lung cancer predicts that MEK-ERK inhibitor combinations can ...

A network meta-analysis of eight randomized trials finds that immune checkpoint inhibitors combined with anti-VEGF therapy outperform other immunotherapy combinations ...

A new review in Cancer Cell International maps how the deubiquitinase USP7 acts as both tumor promoter and suppressor depending ...

New research reveals that the mitochondrial ubiquitin ligase MARCHF5 helps KSHV-transformed lymphoma cells survive by degrading NOXA, the natural antagonist ...

Researchers developed HALO, a machine-learning framework that predicts antibacterial drug synergy from multi-level bioactivity features while exposing how data leakage ...

University of Missouri scientist Ron Mittler is urging biologists to study organisms under multiple simultaneous stressors, arguing that combined stresses ...

A Carrimycin and Azvudine combination showed additive antiviral effects, superior lung protection, and immune benefits in SARS-CoV-2-infected rhesus macaques.

A new review of 28 studies reveals that tigecycline holds strong promise against rapidly growing nontuberculous mycobacteria like M. abscessus, ...

Radiation therapy has long been a cornerstone in the treatment of various forms of cancer, but its role has recently ...

In a groundbreaking study led by Nofal et al., researchers have delved into the intricate world of dermatology, focusing particularly ...

In recent years, the rise of multidrug-resistant bacteria has become a pressing concern in the realm of pediatric medicine. Among ...

The cGAS–STING pathway has emerged as a pivotal mechanism in the landscape of immuno-oncology, particularly in its role in detecting ...