Two Kinases Keep the Fly Circadian Clock on Time When Temperatures Shift
A genetic study in Drosophila shows that the conserved kinases CK2 and DBT preserve circadian temperature compensation through distinct phosphorylation ...
Tag: circadian clock
Circadian Clock Loss May Amplify Growth Hormone Signaling in the Heart
A minireview reports that cardiomyocyte-specific loss of the Bmal1 clock gene increases cardiac growth hormone sensitivity in mice, raising a ...
Body Clock Gene NPAS2 Shields the Diabetic Heart by Keeping Mitochondria Fueled
A new study shows that the circadian clock protein NPAS2 protects the diabetic heart by preserving pyruvate dehydrogenase activity and ...
REV-ERBβ emerges as a non-redundant brake on TH17-driven inflammation
New research reveals that the circadian nuclear receptor REV-ERBβ acts as a distinct, non-redundant negative regulator of pro-inflammatory TH17 cell ...
Body Clock Gene BMAL1 Plummets in Childhood Leukemia, Study Finds
A new study reports that the circadian clock gene BMAL1 and the cell cycle checkpoint regulator WEE1 are significantly downregulated ...
Ancient Alga Keeps Beating Its Daily Rhythm Even When the Sun Never Sets
The charophyte alga Chara braunii shows circadian branchlet movements that persist under dim continuous light but are suppressed at higher ...
Loss of circadian regulation allows for increase in glucose production during lung cancer
New study identifies possible therapeutic target to suppress cancer cell growth Irvine, CA - June 25, 2021 - New research ...
