Researchers Assemble Near Gap-Free Genome for Indigenous Chinese Guanling Cattle
Researchers have generated a near telomere-to-telomere genome assembly for indigenous Chinese Guanling cattle, resolving 31 chromosomes with gaps remaining only ...
Tag: chromatin organization
Super-Resolution Imaging and Deep Learning Accurately Map Subcellular Epigenetic Reorganization
An image-based epigenetic profiling framework combining high-speed super-resolution microscopy with deep learning accurately classified cellular epigenetic states and uncovered chromatin ...
Parasite RNA-Binding Protein TbRRM1 Reveals Its Interaction Network and Binding Platform
A pull-down and docking study in Trypanosoma brucei identified candidate TbRRM1 protein interactors and pinpointed a predicted binding platform spanning ...
How Much Sequencing Is Enough? Study Maps the Depth Limits of Hi-C Chromatin Maps
A systematic subsampling analysis of twelve Hi-C libraries reveals that different chromatin metrics need vastly different sequencing depths, with genome-average ...
Chromatin Architect Satb1 Reveals a Switch That Disarms Tumor-Protective Immune Cells
New research shows the chromatin organizer Satb1 enables regulatory T cells to promote tumor growth while remaining dispensable for preventing ...
Breakthrough AI Unveils 3D Single-Cell Chromosome Architecture
In a groundbreaking advance set to reshape genetic and biomedical research, scientists at the University of Missouri have engineered an ...
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