Mouse Brain Study Uncovers NDN and IDE as Candidate Fragile X Biomarkers
RNA sequencing of fragile X model mice identified the proteins NDN and IDE as strongly upregulated candidate tissue biomarkers, with ...
Tag: Cholinergic neurons
Biofilm-Forming Gut Bacterium Slows Nerve Cell Aging in Worms, Study Finds
A biofilm-proficient Bacillus subtilis strain delayed aging-related structural damage in the cholinergic neurons of C. elegans, with effects enhanced by ...
Single-Cell Sequencing Reveals Mitochondrial DNA Damage in Vulnerable Parkinson’s Neurons
For the first time, researchers have sequenced mitochondrial DNA from individual vulnerable brainstem neurons in Parkinson's disease, revealing extensive deletions ...
Single-Cell Map Reveals Why Some Cholinergic Neurons Age Faster Than Others
Single-nucleus RNA sequencing of the mouse brain reveals that basal forebrain cholinergic neurons undergo uniquely damaging stress-related transcriptional changes with ...
Cholinergic Neurons Control Brain Blood Flow and Fluid
In a groundbreaking study published in Nature Communications, researchers have unveiled an intricate and previously underappreciated role of cholinergic basal ...
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