CDKN2A overexpression linked to radioresistance and immunosuppression in colorectal cancer
Colorectal cancer remains one of the world's most formidable health challenges, ranking as the second leading cause of cancer-related mortality ...
Tag: cancer
AI joins the pediatric oncology nursing team: watching for immunotherapy toxicities before they strike
Children with relapsed leukemia and solid tumors increasingly survive because of a new generation of cancer immunotherapies — CAR-T cells, ...
Blood Test Before Surgery May Reveal Which Gastric Cancer Patients Will Respond to Chemotherapy
A routine blood draw taken before surgery could one day help oncologists predict which gastric cancer patients will benefit from ...
RFWD3 Emerges as a Driver of Intestinal-Type Gastric Cancer Progression
Scientists studying one of the world's deadliest malignancies have identified a molecular player that appears to help intestinal-type gastric cancer ...
Sugar Coats on Death Receptors Act as Molecular Switches Deciding Cell Fate
A new review reveals that sugar chains attached to death receptors act as molecular checkpoints that determine whether cells undergo ...
Immune Signaling Complexes Revealed as Unexpected Master Regulators of the MYC Oncogene
A new perspective article argues that CBM immune signaling complexes regulate the MYC oncogene through transcription, physical binding, and protein ...
NEK2 Drives Trastuzumab Resistance in Gastric Cancer Through m6A Control of FN1
New research reveals that the kinase NEK2 promotes trastuzumab resistance in gastric cancer by boosting WTAP/YTHDF1-dependent m6A modification of FN1 ...
Cancer’s Master Switch: New Map Reveals How Tumors Outsmart Immunotherapy
A sweeping new review in Molecular Cancer maps the PD-1/PD-L1 axis from immune evasion mechanisms to next-generation therapeutics, offering a ...
Optical Biopsy Could Give Breast Surgeons Real-Time Cancer Margins
A comprehensive review finds confocal fluorescence microscopy can image fresh breast tissue at cellular resolution in minutes, with AI and ...
Micro-CT emerges as a promising tool for real-time breast cancer margin checks
Breast-conserving surgery has become the standard of care for most women with early-stage breast cancer, offering survival rates equivalent to ...
One Kinase, Two Tumor Suppressors: The Molecular Triangle That Decides Whether Cancer Therapy Works
Deep inside every dividing cell, a three-way molecular conversation is quietly determining whether a tumor will grow, spread, and shrug ...
Global Training Program Achieves High Agreement in PD-L1 Scoring for Lung Cancer
The clinical significance of the tumor proportion score rests on its role as a gatekeeper for immunotherapy decisions, which is ...
Hidden RNA Molecule Drives Ovarian Cancer by Stabilizing Two Key Oncoproteins
A long non-coding RNA called RBMS3-AS3 has emerged as a powerful molecular accomplice in ovarian cancer, according to a new ...
YouTube exercise videos for lung cancer patients show patchy reliability, study finds
For the millions of people living with lung cancer, exercise is no longer an optional extra. A growing body of ...
New toolkit decodes how cancer genes shatter, circle and resist
AmpliconSuite traces extrachromosomal DNA and focal amplifications across thousands of tumors, revealing formation mechanisms and co-amplification preferences.
Genomic Imprinting’s Hidden Role in Cancer: New Methods Tackle Loss of Imprinting
A new review highlights how loss of imprinting drives tumour growth and why emerging single-cell, spatial, and long-read methods may ...
Rewiring the Tumor: How Cancer Metabolism Is Becoming Medicine’s Next Target
The concept of metabolic reprogramming as a defining feature of malignancy has evolved considerably since its early description, when proliferating ...
MicroRNA and ER Stress Markers Track Prostate Cancer Aggressiveness in New Study
A Turkish clinical study links miR-188-5p and ER stress markers GRP78 and CHOP to prostate cancer aggressiveness, with a combined ...
Income Shapes Who Survives Disease in Sweden, Landmark Study of 100 Conditions Finds
A study of nearly 6.85 million Swedes found that people in the lowest income quartile had worse ten-year survival than ...
Antimalarial drug mefloquine triggers ferroptosis in colorectal cancer, study finds
The concept of drug repurposing, sometimes called repositioning, has become an increasingly attractive strategy in oncology because established medicines already ...
