Tag: biomarkers

A study of 107 people found that ENHO gene expression was higher in prediabetes and lower in type 2 diabetes, ...

An exploratory analysis of a phase 3 COVID-19 trial found that a composite score combining baseline interleukin-6 levels and neutrophil ...

A 2026 mini review finds that CT is established for anatomical assessment and surgical planning after neoadjuvant immunotherapy in resectable ...

Researchers have identified seven candidate biomarker genes for Parkinson's disease by combining transcriptomic data analysis, Mendelian randomization, and machine learning, ...

A longitudinal study of people carrying ALS genetic variants found mild cognitive impairment, mainly affecting language and executive functioning, in ...

A machine learning tool combining quantitative muscle MRI fat fractions with clinical scores predicts when boys with Duchenne muscular dystrophy ...

A new Perspective proposes a unified pharmacological-toxicological framework treating ferroptosis, mitochondrial stress and redox imbalance as one axis governing both ...

A new narrative review argues that human brain organoids are reshaping stroke research by exposing human-specific injury mechanisms that animal ...

A large prospective UK Biobank study of 52,584 adults identified nine plasma proteins, led by neurofilament light chain, that predict ...

In cognitively unimpaired adults aged 55 to 75, plasma amyloid-beta levels were consistently associated with shorter and less dense frontal ...

A paired-sample study of 20 multiple sclerosis patients found that freezing changed serum neurofilament light chain measurements by different amounts ...

A small proof-of-concept study found that adolescents with repaired tetralogy of Fallot and moderate-severe right ventricular dilation on cardiac MRI ...

A multi-cohort re-analysis of melanoma transcriptomes and single-cell immune data links coordinated checkpoint-gene expression to longer overall survival, treatment-related immune ...

An integrative transcriptomic study has identified an extracellular matrix and perineuronal net-high astrocyte state in major depressive disorder, along with ...

A BMC Pediatrics study finds that a random forest model combining serum creatinine and cystatin C, further improved by adding ...

A review proposes that mitochondrial dysfunction across cartilage, synovium, subchondral bone and neural compartments forms a shared pathological network linking ...

A 69-microRNA signature measured in blood exosomes classified Parkinson's disease with an AUC of 0.952 across cohorts, while multi-omics analyses ...

Researchers combined high-purity vesicle proteomics, computational gene expression analysis and optimized immuno-isolation to validate NRXN3 as a candidate marker for ...

A review proposes that ovarian aging is a progressive reorganization of immune, metabolic, and endocrine networks linking the ovary to ...

A 2026 review finds that multi-agonist obesity drugs can produce substantial weight loss, but biomarker and pharmacogenomic tools are not ...