Acupuncture Eases Migraines but Leaves Key Biomarker CGRP Unchanged
A prospective pilot study of 52 patients with episodic migraine found significant clinical improvements after 10 sessions of manual acupuncture, ...
Tag: biomarker
Vimentin Emerges as a Powerful Prognostic Marker in Triple-Negative Breast Cancer
A retrospective cohort study from Indonesia's national referral hospital links vimentin expression to dramatically shorter survival in triple-negative breast cancer ...
Small RNA Molecule Shows Promise Against Ovarian Cancer Chemoresistance
A new study shows that the microRNA-197-3p molecule, which is depleted in ovarian cancer, directly suppresses the collagen protein COL4A6 ...
Inflammation Gene Variant May Shape Survival After Rectal Cancer Therapy Choice
An exploratory analysis of a randomized trial in locally advanced rectal cancer found that an IL1B gene variant was linked ...
Why Antigen Expression Alone Cannot Predict Response to B7-H3-Targeted Cancer Therapy
A new review argues that B7-H3 positivity measured by immunohistochemistry is necessary but not sufficient to predict response to antibody-drug ...
White Matter Is Not Silent: Hidden Brain Networks Shift Early in Alzheimer’s Disease
A large resting-state fMRI study of 789 ADNI participants shows that white matter functional networks are measurably and selectively disrupted ...
A Hidden RNA Splice Variant May Predict Relapse After CD19 CAR-T Therapy
Danish researchers report that low-level skipping of CD19 exon 2, detectable in pre-treatment RNA-sequencing data, correlates with relapse after anti-CD19 ...
Blood Urea Nitrogen Emerges as a Powerful Predictor of Survival in Critically Ill Multiple Myeloma Patients
A retrospective cohort study using the MIMIC-IV database found that elevated blood urea nitrogen within 24 hours of ICU admission ...
New Python Package Puts Biomarker Discoveries to the Test Before They Reach the Clinic
A new open-source Python package called ROOFS benchmarks multiple feature selection methods on a researcher's own data, evaluating predictive performance ...
Rat Incisors Reveal How Diabetes Drives Inflammatory Cell Death in Teeth
New research links slowed incisor growth in diabetic rats to oxidative stress and RIPK3–MLKL necroptosis signaling within the dental pulp.
Sequencing Read Counts Could Flag the Most Infectious Tuberculosis Patients
Pulmonary tuberculosis remains one of the world's most stubborn infectious diseases, and a central challenge for clinicians is telling apart ...
Low Butyrylcholinesterase Activity in Dogs Signals Inflammation but Trails CRP as a Biomarker
A large Bern study of 950 dogs shows low plasma butyrylcholinesterase activity is associated with SIRS, sepsis, and poor survival, ...
Machine Learning Biomarker BioWaitIndex Predicts Liver Transplant Waitlist Outcomes Beyond MELD
A machine learning-derived composite biomarker built from twelve routine clinical measurements predicted waitlist mortality and transplantation in liver transplant candidates ...
Blood Test for Bacterial Infection Fails as a Diagnostic Tool but Excels at Tracking Sepsis Risk in Ethiopian Hospital Study
A prospective study of 210 hospitalized adults in Southwest Ethiopia found that admission procalcitonin performed poorly for diagnosing bacterial infection ...
GDF-15: The Stress Hormone That Decides When We Eat, Burn, and Waste Away
A new review maps how the stress hormone GDF-15 integrates appetite, muscle metabolism, inflammation, and iron homeostasis, positioning it as ...
Cancer Protein LGALS3BP Reshapes the Cargo of Neuroblastoma Extracellular Vesicles
New research links the secreted glycoprotein LGALS3BP to selective enrichment of microRNAs and the RNA-binding protein SRSF1 in neuroblastoma extracellular ...
Hormone Response to Mild Stress Predicts PTSD-Like Vulnerability in Female Rats
A rat study shows that how much corticosterone an animal releases during a mild stressor can forecast trauma-related behaviors weeks ...
Scaffold Protein LAMB1 Drives Esophageal Cancer Growth Through JAK2/STAT3 Pathway
New research shows that the extracellular matrix protein LAMB1 accelerates esophageal squamous cell carcinoma by activating JAK2/STAT3 signaling, suggesting it ...
Tiny Brainstem, Big Clues: MRI Measurements Predict Development in Extremely Preterm Infants
A new study establishes the first reference values for brainstem size on MRI in extremely preterm infants and links smaller ...
Simple Blood Test Marker Signals Hidden Lymph Node Spread in Early Lung Cancer
A meta-analysis of thirty studies finds that elevated preoperative CEA is strongly associated with occult lymph node metastasis in clinical ...
