BRG1 Protein Drives Diabetic Corneal Nerve Damage Through Glycolytic Reprogramming in Mice
Scientists discovered that the chromatin remodeler BRG1 drives diabetic corneal neuropathy in mice by activating PI3K/AKT signaling to fuel excessive ...
Tag: 2-deoxy-D-glucose
Lactate-Driven Histone Modification Accelerates Spinal Disc Degeneration by Suppressing Protective CD248
Researchers have discovered that lactate accumulation in degenerated spinal discs induces histone H3K18 lactylation, which recruits the repressor SMARCA5 and ...
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