• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Friday, October 24, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

Smoking decreases MAIT cells, implicated in the pathology of autoimmune diseases

Bioengineer by Bioengineer
May 2, 2017
in Science News
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

New research published in the May 2017 issue of the Journal of Leukocyte Biology provides another reason why smoking tobacco is harmful. In the report, researchers from Denmark show that smokers have reduced levels of mucosal-associated invariant T (MAIT) cells, a cell type involved in autoimmune diseases. Not only does this information shed more light on the effects of smoking, but it also reveals possible strategies to mitigate these effects.

"We believe that our study represents an important contribution to the understanding of systemic immune cell alterations in smokers," said Cecilie Ammitzbøll, M.D., Ph.D., a researcher involved in the work from the Danish Multiple Sclerosis Center in Copenhagen, Denmark. "From our findings we hope that focused research in specific cell populations might reveal pathogenic mechanisms contributing to the understanding of diseases associated with smoking."

To make their discovery, scientists investigated circulating immune cells from cohorts of healthy individuals and patients with multiple sclerosis. The researchers looked for differences in smokers compared with non-smokers and found that the frequencies of certain cell types were altered. These findings were evident in both healthy individuals and patients with multiple sclerosis. Further, by using two different techniques, the scientists found that T cells from smokers were not more easily activated when they encountered foreign- and self-antigens.

"It is clear that smoking is detrimental to overall health and can predispose to many diseases," said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology. "These new studies shed like on how smoking can also influence the immune system, an effect that may have implications in autoimmunity and also in other settings such as cancer and chronic inflammatory diseases."

###

The Journal of Leukocyte Biology publishes peer-reviewed manuscripts on original investigations focusing on the cellular and molecular biology of leukocytes and on the origins, the developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes and other cells involved in host defense and inflammation. The Journal of Leukocyte Biology is published by the Society for Leukocyte Biology.

Details: Cecilie Ammitzbøll, Lars Börnsen, Jeppe Romme Christensen, Rikke Ratzer, Birgitte Romme Nielsen, Helle B. Søndergaard, Marina R. von Essen, and Finn Sellebjerg. Smoking reduces circulating CD26hiCD161hi MAIT cells in healthy individuals and patients with multiple sclerosis. J. Leukoc. Biol. May 2017 101:1211-1220; doi:10.1189/jlb.3A0616-267R ; http://www.jleukbio.org/content/101/5/1211.abstract

Media Contact

Cody Mooneyhan
[email protected]
301-634-7104
@fasebopa

http://www.faseb.org

############

Story Source: Materials provided by Scienmag

Share12Tweet7Share2ShareShareShare1

Related Posts

Study Reveals Sharp Increase in Severe Diverticulitis Cases Among Younger Americans

October 24, 2025
Cockroach Infestation Associated with Elevated Home Allergen and Endotoxin Levels

Cockroach Infestation Associated with Elevated Home Allergen and Endotoxin Levels

October 24, 2025

Assessing Antibiotic Quality in Addis Ababa

October 24, 2025

Pediatric Respiratory Co-Infection: Immune Response Study Protocol

October 24, 2025
Please login to join discussion

POPULAR NEWS

  • Sperm MicroRNAs: Crucial Mediators of Paternal Exercise Capacity Transmission

    1280 shares
    Share 511 Tweet 320
  • Stinkbug Leg Organ Hosts Symbiotic Fungi That Protect Eggs from Parasitic Wasps

    309 shares
    Share 124 Tweet 77
  • ESMO 2025: mRNA COVID Vaccines Enhance Efficacy of Cancer Immunotherapy

    188 shares
    Share 75 Tweet 47
  • New Study Suggests ALS and MS May Stem from Common Environmental Factor

    133 shares
    Share 53 Tweet 33

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Study Reveals Sharp Increase in Severe Diverticulitis Cases Among Younger Americans

Cockroach Infestation Associated with Elevated Home Allergen and Endotoxin Levels

Assessing Antibiotic Quality in Addis Ababa

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 66 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.