• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Friday, September 26, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Research Brief: Older adults often prescribed meds linked to higher side effect risks

Bioengineer by Bioengineer
March 27, 2018
in Health
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Drugs with high-risk anticholinergic properties can lead to risks of developing serious adverse events, such as cognitive impairment, falls, dementia, and even mortality in older adults. Yet, relatively little is known about prescribing trends of high-risk anticholinergic medications in the United States of America.

Researchers in the University of Minnesota College of Pharmacy conducted a repeated cross-sectional analysis of the 2006-2015 National Ambulatory Medical Care Survey to understand more.

They found that physicians' prescribing behavior remained stable over time, and these drugs were prescribed in about six percent of visits over a ten-year period. The findings were recently published in the Journal of the American Geriatrics Society.

"High-risk anticholinergic prescribing should be avoided because there are safer alternative medications for older adults," said the lead study author, Greg Rhee, Ph.D., M.S.W., adjunct assistant professor in the College of Pharmacy.

Anticholinergic medications block the neurotransmitter acetylcholine, which is part of the nervous system and plays a role in involuntary muscle contractions. These drugs are often prescribed for urinary, respiratory and gastrointestinal disorders. They're also often used to treat depression.

"Older adults are vulnerable to these medications due in part to physiological changes as they age. In general, older adults have a higher likelihood of developing adverse drug events from taking multiple medications," Rhee said.

The research team investigated whether prescribing patterns of high-risk anticholinergic drugs have changed over time and whether these patterns vary by physician specialty and anticholinergic class among older adults in their office-based care. They also estimated demographic and clinical correlates factors independently associated with these high-risk anticholinergic medication prescriptions.

They found:

  • six percent of doctors' visits studied within the survey period listed an anticholinergic medication – suggesting he prescribing pattern varies by physician specialty (e.g., psychiatrists and urologists had higher rates of listing an anticholinergic medication);
  • that by medication class, antidepressants were the most prevalent among anticholinergic drugs prescribed to older adults;
  • women were more likely to receive high-risk anticholinergic prescriptions;
  • patients from the South were more likely to receive high-risk anticholinergic prescriptions;
  • patients with prescribed six or more medications had a greater likelihood of being prescribed high-risk anticholinergic prescriptions.

The research team acknowledged the study had limitations. The survey does not include emergency department or hospital visits. Therefore, the study results may actually underestimate the full impact.

Rhee noted that the prevalence of high-risk anticholinergic prescriptions was stable over time, but varied by physician specialty and drug class. He recommends increasing awareness of potential adverse effects and encouraging providers to prescribe less-risky medications.

###

Media Contact

University Relations
[email protected]
612-624-5551
@UMNews

http://www.umn.edu

https://twin-cities.umn.edu/news-events/research-brief-older-adults-often-prescribed-meds-linked-higher-side-effect-risks

Related Journal Article

http://dx.doi.org/10.1111/jgs.15357

Share12Tweet7Share2ShareShareShare1

Related Posts

Safeguarding Our Healthcare Heroes: Strategies to Boost Vaccination Among Medical Workers Amid Rising Measles Cases

September 26, 2025

New Deep Learning Model Classifies Circulating Tumor Cells

September 26, 2025

Rituximab Enhances Nephrotic Syndrome Treatment in Children

September 26, 2025

Transforming Equity in Learning Health Systems Through Implementation

September 26, 2025
Please login to join discussion

POPULAR NEWS

  • New Study Reveals the Science Behind Exercise and Weight Loss

    New Study Reveals the Science Behind Exercise and Weight Loss

    78 shares
    Share 31 Tweet 20
  • Physicists Develop Visible Time Crystal for the First Time

    71 shares
    Share 28 Tweet 18
  • Scientists Discover and Synthesize Active Compound in Magic Mushrooms Again

    55 shares
    Share 22 Tweet 14
  • Tailored Gene-Editing Technology Emerges as a Promising Treatment for Fatal Pediatric Diseases

    51 shares
    Share 20 Tweet 13

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Advancements in Lightweight UAV Object Detection: Exploring Reparameterized Convolutions and Shallow Fusion Networks

Safeguarding Our Healthcare Heroes: Strategies to Boost Vaccination Among Medical Workers Amid Rising Measles Cases

New Deep Learning Model Classifies Circulating Tumor Cells

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.