New atlas reveals mesenchymal diversity in human gut and organoids
Beneath every square centimeter of the human small intestine lies a hidden scaffold of cells that has quietly governed one of the most dynamic tissues...
NEWS INDEX
New spatial transcriptomics method maps RNA isoforms across primate brain cells
For two decades, neuroscientists have been building ever finer maps of gene activity in the brain, charting which genes switch on in which cells, in...
Transcription factors steer distinct pancreatic cancer cell states and drug dependencies
Pancreatic cancer has earned its grim reputation the hard way. Fewer than one in eight patients survives five years beyond diagnosis, and while outcomes for...
Lewis acids turn degradation into useful doping for organic semiconductors
For decades, chemists working on electronic materials have treated molecular decomposition as the enemy—a process to be suppressed with every stabilizing trick at their disposal....
Tuberculosis interventions deliver major global impact at affordable cost
Tuberculosis has quietly reclaimed a title no pathogen should want: the world’s deadliest infectious disease. According to the World Health Organization, 10.8 million people fell...
Gut microbiome imbalance expands inflammatory dendritic cells, triggering early autoimmunity
Long before lupus announces itself with swollen joints and damaged kidneys, long before type 1 diabetes destroys enough insulin-producing cells to push blood sugar upward,...
Nanoscale imaging reveals magnetic brightening of spin-polarized helical edge modes in ZrTe5
Physicists have, for the first time, directly imaged the exotic edge currents that race along the boundary of zirconium pentatelluride, one of the most tantalizing...
Tuning 2D perovskites yields efficient, stable perovskite-silicon tandem solar cells
Researchers have engineered a molecular-level solution to one of the most stubborn efficiency bottlenecks in perovskite solar technology, achieving a certified power conversion efficiency of...
Quantum Hall antidot acts as a fractional charge meter
Physicists have demonstrated a new type of extremely sensitive charge detector built on the quantum Hall effect, capable of resolving charge in fractional units of...
Portable SERS sensor measures full-range underwater pH directly in the field
Few measurements seem as straightforward as dipping a probe into water and reading its pH. Fewer still survive intact where chemists most want to take...
Human TOM and TIM22 complexes join forces to import mitochondrial carriers
You are the science news desk of a major English-language science magazine. Complete the task immediately. Never ask the reader what to do, never offer...
Researchers reveal guiding principles for electrochemical synthesis of multimetallic nanocrystals
For much of the past three decades, coaxing nanocrystals made of more than one metal into existence has been closer to alchemy than to engineering....
Deep Learning Powers White Blood Cell Classification, Comprehensive Review Finds
In laboratories around the world, a quiet revolution has been unfolding under the microscope. The differential white blood cell count—a technique that has guided physicians...
Federated Learning Could Train AI Language Models Without Sharing Private Data
Training a state-of-the-art large language model has always meant one thing: gathering enormous amounts of text in one place. But the texts that matter most...
Mol2Image turns drug molecular descriptors into images to predict interactions
In a development that could reshape how the pharmaceutical world screens for hazardous drug combinations, researchers have unveiled Mol2Image, a deep learning framework that converts...
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