Modulating T-cell metabolism uncovers new technology for enhancing immunotherapy
PHILADELPHIA -- (Sept. 11, 2017) -- T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients...
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UCLA opens clinical trial for cancers with the NY-ESO-1 tumor marker
Credit: Photo courtesy of: UCLA Jonsson Comprehensive Cancer Center Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at...
DNA looping architecture may lead to opportunities to treat brain tumors
Credit: Baylor College of Medicine The discovery of a mechanism by which normal brain cells regulate the expression of the NFIA gene, which is important...
The 2017 Balzan Prizewinners announced today in Milan
Milan, 11 September 2017 - The names of the 2017 Balzan Prizewinners were disclosed today in a public announcement: Aleida and Jan Assmann (Germany), Universities...
Savings less than expected for generic oral chemotherapy
CHAPEL HILL -- A study by researchers at the University of North Carolina Eshelman School of Pharmacy and Lineberger Comprehensive Cancer Center determined the cost...
Revolutionary process could signal new era for gene synthesis
Credit: Karl Harrison A team of scientists led by the University of Southampton has demonstrated a groundbreaking new method of gene synthesis - a vital...
Combination targeted adjuvant therapy doubles relapse-free survival in stage III melanoma
LUGANO-MADRID, 11 September, 2017 - Combination targeted adjuvant therapy with dabrafenib and trametinib doubles relapse-free survival in patients with stage III BRAF-mutant melanoma, according to...
Adjuvant nivolumab superior to ipilimumab in surgically resected stage III/IV melanoma
LUGANO-MADRID, 11 September, 2017 - Adjuvant nivolumab is superior to standard of care ipilimumab in patients with surgically resected stage III/IV melanoma who are at...
KEYNOTE-040 evaluates pembrolizumab in head and neck cancer
LUGANO-MADRID, 11 September, 2017 - Immunotherapy with the checkpoint inhibitor pembrolizumab may be a better option than standard treatments for patients whose head and neck...
Debate on duration of colon cancer adjuvant chemotherapy takes centre stage at ESMO 2017
LUGANO-MADRID, 11 September, 2017 - The debate on whether to shorten adjuvant chemotherapy for colon cancer from six to three months takes centre stage today...
Ramucirumab plus docetaxel improves progression-free survival in urothelial cancer
LUGANO-MADRID, 10 September, 2017 - Ramucirumab plus docetaxel improves progression-free survival in patients with advanced or metastatic urothelial cancer who have progressed on platinum-based chemot..
Mature results favor pembrolizumab as second-line treatment for bladder cancer
LUGANO-MADRID, 10 September, 2017 - Mature results from the KEYNOTE-045 trial to be presented today at the ESMO 2017 Congress in Madrid (1) have confirmed...
Does health insurance status affect childhood cancer survival?
A new study examines whether insurance status may affect survival in children diagnosed with cancer. Published early online in CANCER, a peer-reviewed journal of the...
Ambry Genetics & NorthShore University HealthSystem partner to advance precision medicine
Credit: Jonathan Hillenbrand Aliso Viejo, CA and Evanston, IL (September 12, 2017): Ambry Genetics (Ambry), a leading clinical genetics-testing lab, and NorthShore University HealthSystem's (N..
Scientists discover genetic timetable of brain’s aging process
The programme controls how and when brain genes are expressed at different times in a person's life to perform a range of functions, the study...