Insulin release is controlled by the amount of Epac2A at the secretory vesicles
Specialized beta cells in the pancreas release the hormone insulin to control our blood glucose levels, and failure of this mechanism is central to the...
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Bariatric surgery, medication/lifestyle modification: Which has better long-term effect on diabetes
July 7, 2017, Cleveland: A team of Cleveland Clinic researchers is leading a first-of-its-kind multicenter clinical trial to assess the long-term outcomes of bariatric/metabolic surgery...
NYU researchers identify promising target to protect bone in patients with diabetes
Researchers at New York University College of Dentistry (NYU Dentistry) have described a new target that may open the door to developing therapies for preventing...
Drinking alcohol while pregnant could have transgenerational effects
RIVERSIDE, Calif. - Soon-to-be mothers have heard the warning - don't drink while pregnant. The Centers for Disease Control and Prevention (CDC) has issued numerous...
Synthesis of internal gem-diborylalkanes by copper-catalyzed double hydroboration
Geminal organometallic reagents have attracted considerable attention due to their unique activity. Among them, gem-diboryl compounds are particularly valuable due to their stability, no-toxicity, and..
Well-being in later life: The mind plays an important role
(Helmholtz Zentrum München - German Research Center for Environmental Health) Well-being in later life is largely dependent on psychosocial factors. Physical impairments tend to play...
Childhood obesity major link to hip diseases
New research from the University, published in the Archives of Disease in Childhood journal, shows a strong link between childhood obesity and hip diseases in...
Obstructing the ‘inner eye’
Credit: Jan-Peter Kasper/FSU "In our project, we are looking at how the brain makes hypnotic states possible," explains Professor Wolfgang Miltner, who has been working...
SMAD4 loss is associated with cetuximab resistance and induction of MAPK/JNK activation in HNC
Credit: Insilico Medicine Summary: Cetuximab, an anti-EGFR monoclonal antibody and the only FDA-approved targeted therapy against advanced head and neck squamous cell carcinoma (HNSCC), has...
Simple test predicts return of bladder cancer
Scientists have devised a simple test for an earlier and more accurate warning of returning bladder cancer than existing methods, according to research* published in...
Heavier birthweight linked to increased risk of obesity in early school-aged children
In a recent study, babies who were large at birth had an increased likelihood of being obese when they were in kindergarten to second grade...
‘Educating’ patients’ immune cells may help combat diabetes
New research reveals that a treatment called Stem Cell Educator therapy is safe and effective for treating type 1 and type 2 diabetes. The therapy...
Sand in public playgrounds may play a role in transmitting infections
Investigators have revealed that the Gram-positive, anaerobic bacterium Clostridium difficile is widely distributed in soil samples from children's and dogs' sandboxes located within the met..
Teaching old drugs new tricks in the fight against infectious diseases
A new article looks at how currently available drugs for various conditions might be repurposed alone or in combination with other drugs to treat infectious...
Family-based treatments may help address obesity in children
Researchers found that a family-based treatment for obesity in children--which included nutritional advice, exercise, and behavioral counseling--was effective. The treatment lasted for about a year..
