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PHILADELPHIA - In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah™ (formerly known as...

Landmark CAR-T cancer study published in the New England Journal of Medicine

Credit: Loyola Medicine MAYWOOD, IL - Loyola University Medical Center is the only Chicago center that participated in the pivotal clinical trial of a groundbreaking...

Sequencing offers clues to progression toward multiple myeloma

ATLANTA -- Researchers at Dana-Farber Cancer Institute have carried out the largest genomic analysis of patients with smoldering multiple myeloma (SMM), a precursor to full-blown...

Rapid responses, few adverse effects in targeted agent in Phase1 trial in rare blood disorder

ATLANTA - In a Phase 1 trial, patients with an advanced or aggressive form of systemic mastocytosis (AdvSM), a rare blood disorder, had rapid and...

Tracking how multiple myeloma evolves by sequencing DNA in the blood

ATLANTA - Although people with multiple myeloma usually respond well to treatment, the blood cancer generally keeps coming back. Following genetic changes in how the...

Physical activity data, emojis on Apple Watch correlated with patient-reported outcomes

ATLANTA - In findings presented to the American Society of Hematology, Mayo Clinic researchers found that using emojis instead of traditional emotional scales were helpful...

Study explores use of checkpoint inhibitors after relapse from donor stem cell transplant

ATLANTA - Immunotherapy agents known as checkpoint inhibitors have shown considerable promise in patients with hematologic cancers who relapse after a transplant with donor stem...

For leukemia patients, transfusion needs may delay hospice care

Toward the end of life, some leukemia patients depend on blood transfusions to ease their suffering. Unfortunately, the likelihood that transfusions won't be accessible through...

Immunotherapy drug nearly eliminates severe acute graft-versus-host disease

Credit: Seattle Children's SEATTLE - Dec. 9, 2017 - Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th...

Study results offer another boon for PARP inhibitors in treatment of advanced breast cancer

SAN ANTONIO - Patients with certain advanced hereditary breast cancers may have new treatments options on the horizon, according to two studies presented this week...

For women with genetic risk, bi-annual MRI beats mammograms

Intensive surveillance including a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) exam every six months was far more effective in detecting breast cancer in younger women...

Lymph node surgery may raise risk of arm morbidity in younger women

SAN ANTONIO -- Younger breast cancer patients who underwent axillary lymph node dissection were more likely to experience arm swelling and decreased range of arm...

Family members without inherited mutation have increased risk of melanoma

In families who carry certain inherited mutations that increase the risk for melanoma, members who do not carry the mutation also have an increased risk...

Molecular beacon signals low oxygen with ultrasound

Credit: Video courtesy of Jefferson Chan, University of Illinois CHAMPAIGN, Ill. -- Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers...

ERC grant: €2 million for synthetic biology at TU Darmstadt