Two classes of GGAA-microsatellites in a Ewing sarcoma context
COLUMBUS, Ohio - In a study published in PLOS ONE, researchers describe two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation...
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Researchers find genetic pathways to individualized treatment for advanced prostate cancer
ROCHESTER, Minn. -- Researchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating...
Infertility linked to higher risk of death among women
SAN ANTONIO -- Women with a history of infertility have a 10 percent increased risk of death compared to those without reported infertility struggles, according...
In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors
Credit: University of Colorado Cancer Center Two University of Colorado Cancer Center studies were presented this weekend at the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics...
Breast cancer patients forego post-surgery treatment due to mistrust, study suggests
Nearly one-third of women with breast cancer went against their doctor's advice and chose not to begin or complete the recommended adjuvant anti-cancer therapy to...
It is time for a concerted European approach to defeat cancer
LUGANO, 31 October 2017. ESMO President, Fortunato Ciardiello, has contributed an editorial on the priorities for future cancer research, to The Lancet Oncology (1) with...
Brain tumour’s ‘addiction’ to common amino acid could be its weakness
Starving a childhood brain tumour of the amino acid glutamine could improve the effect of chemotherapy, according to an early study led by Queen Mary...
Mandated coverage for fertility preservation featured in NEJM
This summer, it was announced that Rhode Island became the first state to pass a law explicitly requiring coverage for fertility preservation prior to gonadotoxic...
Gut microbiome may make chemo drug toxic to patients
Credit: Albert Einstein College of Medicine Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of...
Breast cancer researchers track changes in normal mammary duct cells leading to disease
(TORONTO, Canada - Nov. 1, 2017) - Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumours to...
PARP inhibitor may be effective against some TNBC lacking BRCA mutations
Bottom Line: The investigational PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) that had BRCA mutations and also those...
Marine scientists discover kleptopredation — a new way of catching prey
Credit: Gabriella Luongo When it comes to feeding time sea slugs are the pirates of the underwater world - attacking prey that have just eaten...
Could the Neolithic Revolution offer evidence of best ways to adapt to climate change?
Human behaviour during the last intense period of global warming might offer an insight into how best to adapt to current climate change, a study...
Rutgers-led research could revolutionize nuclear waste reprocessing and save money
Credit: Hao Wang/Rutgers University-New Brunswick Seeking a better way to capture radioactive iodides in spent nuclear reactor fuel, Rutgers-New Brunswick scientists have developed an extremely...
In vitro tissue microarrays for quick and efficient spheroid characterization
Credit: Image courtesy of Ivanov et al. An SLAS Discovery original research report entitled "In Vitro Tissue Microarrays for Quick and Efficient Spheroid Characterization" describes...
