Study shows simple, computationally-light model can simulate complex brain cell responses
The brain is inarguably the single most important organ in the human body. It controls how we move, react, think and feel, and enables us...
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AF2Complex: Researchers leverage deep learning to predict physical interactions of protein complexes
From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible.Credit: (Photo: Jess...
A key brain region for substance use disorders now has a searchable atlas of distinct cell populations
BIRMINGHAM, Ala. – In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations...
Unlocking complex workings of the biological clock
Scientists want to increase their understanding of circadian rhythms, those internal 24-hour biological clock cycles of sleeping and waking that occur in organisms, ranging from...
Decoding a direct dialog between the gut microbiota and the brain
Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions. Scientists from the Institut Pasteur (a partner research...
From cell fat to cell fate
How does a cell “decide” what type of cell to become? The question of “cell fate” has been explored for decades now, especially in the...
Key signaling pathway in immune cells could be new Alzheimer’s target
Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer’s and some other neurodegenerative...
Energy-burning brown fat less active in boys with obesity
Hamilton, ON (April 14, 2022) – A study at McMaster University has found that brown adipose tissue (BAT) is less active in boys with obesity...
The opportunity cost of conservation
In 2019, a landmark report gave the world its first report card on biodiversity loss. There was one crystal clear conclusion: human actions threaten more...
Vitamin E can boost immunotherapy responses by reinvigorating dendritic cells
HOUSTON ― Combining a retrospective analysis of clinical records with in-depth laboratory studies, researchers at The University of Texas MD Anderson Cancer Center have discovered...
Research reveals human-driven changes to distinctive foraging patterns in North Pacific Ocean
The first large-scale study of its kind has uncovered more than 4,000 years’ worth of distinctive foraging behaviour in a species once driven to the...
Colon cancer: How mutation of the APC gene disrupts lymphocyte migration
In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but...
Scientists identify novel approach to preventing seizures
Scientists at Trinity College Dublin have announced a significant advance in our understanding of epilepsy, as they have identified a potential method of preventing damaging seizure...
UNH research finds a genomic time machine in sea sponges
DURHAM, N.H.—Sponges in coral reefs, less flashy than their coral neighbors but important to the overall health of reefs, are among the earliest animals on...
Sports participation by transgender youth: Providers’ perspectives
In a new study, providers of care to transgender youth were against the rising tide of legislation restricting participation of transgender youth in gender-segregated sports....