Covalent PFKL activator suppresses tumor growth
Cancer cells are often described as metabolic opportunists: they reshape the way they use nutrients so they can grow rapidly, survive stress and build new...
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Macrophage-to-myofibroblast transition-derived itaconate drives lung cancer bone metastasis via HSPA8
Lung cancer’s spread to bone is one of the most destructive stages of the disease, often causing severe pain, fractures, spinal cord compression and dangerous...
USC Engineering Students Team Up With Trojan Football
As college football season approaches, a team of students and recent alumni at the USC Viterbi School of Engineering is undertaking a project that could...
Scientists transform notoriously hated plastic into high-value lubricant
Virginia Tech researchers have developed a chemical process that turns discarded polyvinyl chloride, or PVC, into polyalphaolefin, a high-performance material widely used in lubricants such...
Cold Spring Harbor, Northwell Health lead development of 150+ cancer treatment models
A decade-long international effort has produced the largest publicly available collection of patient-derived cancer organoids to date, giving researchers a powerful new way to study...
Human brain tissue reveals how electrical stimulation changes neurons and gene activity
A team of researchers has used living human brain tissue to reveal how deep brain stimulation changes the activity of individual brain cells and activates...
Cancer Dependency Map Adds Next-Generation 3D Cancer Models
For nearly a decade, the Cancer Dependency Map, known as DepMap, has helped researchers identify the genetic weaknesses that cancer cells rely on to survive....
Early NT-proBNP Versus Echocardiographic PLASE Score for Predicting PDA Surgery
A new study in Pediatric Research is examining whether a simple blood test taken early in life can predict which newborns with a patent ductus...
Weight Trajectories Linked to Better Head Growth in Infants Under 32 Weeks
For babies born extremely early, the first weeks outside the womb can resemble a biological balancing act. They must maintain temperature, tolerate feeding, avoid infection...
EPFL’s Ursula Röthlisberger Wins Michele Parrinello Award for Computational Physical Science
Open-access scholarly publisher MDPI has named Professor Ursula Röthlisberger of the École Polytechnique Fédérale de Lausanne (EPFL) as the recipient of the 2026 Michele Parrinello...
Biofortified millet boosts toddler nutrition without supplement side effects
Iron deficiency affects about one in four people worldwide, with young children among those at greatest risk. In early life, inadequate iron can impair brain...
IL-1 Signaling Strengthens Mucosal Defense Against Systemic Candida albicans Infection
A new study published in Nature Microbiology identifies signalling pathways from the interleukin-1 family as key drivers of mucosal defence during systemic infection with the...
How BRI1 Receptors Recognize Diverse Brassinosteroid Hormones
Brassinosteroids are among the most influential hormones in plant biology, yet the molecular logic that allows plants to recognize such a chemically diverse family of...
Hippocampal Wiring Study Finds Graded Mossy Fiber Inputs and Targeted Inhibition
The hippocampus is often portrayed as a single memory machine, but a new connectomics study suggests that one of its most important circuits is organized...
Palmitate Drives Liver Metastasis by Suppressing Neutrophils’ Antitumour Activity
Liver metastases are among the most difficult complications of advanced cancer. Unlike many other organs, the liver is continuously exposed to nutrients arriving from the...