High-throughput proteomics and machine learning revealed that cereblon-recruiting androgen receptor degraders inhibit mitochondrial complex I, and guided linker modifications that produced safer compounds with superior...
A Nature Aging study shows that earlier thymic involution and accelerated conversion of naive CD8+ T cells into short-lived virtual memory cells shrink lymph nodes...
Researchers at the Chinese Academy of Sciences have developed a factorized-gating mixture-of-experts framework that blends regime-specific turbulence specialists to deliver accurate, interpretable predictions across diverse...
New research shows that metformin and phenformin suppress cysteine deprivation-induced ferroptosis in cancer cells by dampening mitochondrial hyperpolarization, oxygen consumption, and iron accumulation.
Researchers have unveiled a security framework that protects privacy-preserving, secret-shared databases against malicious data owners by combining verifiable secret sharing, zero-knowledge proofs, and lightweight query-level...
Researchers in India have developed a smartphone-based colorimetric sensor using citrate-capped gold nanoparticles that detects the organophosphate pesticide ethion in water and soil at detection...
A review and international survey of musculoskeletal infection care find no evidence for routine isolation of patients without drug-resistant organisms, exposing a wide gap between...
The first comprehensive study of Türkiye's Lalahan sheep shows the new crossbred genotype delivers efficient growth and lean carcasses, with 40 kilograms identified as the...
A microfluidic model built from primary human placental cells shows how cadmium undermines placental function at doses that cause no visible cell death and identifies...
University of Illinois researchers have built a scalable chip-based quantum memory that stores photons for over a microsecond using erbium-doped thin-film lithium niobate and atomic...
A new citizen science project called Who Eats Whom has turned thousands of iNaturalist photographs into a searchable global food web connecting nearly 2,000 species...
The Journal of Pharmaceutical Investigation has announced a January 2027 special issue, led by three Korean guest editors, dedicated to translational advances in pharmaceutical dosage...
A large retrospective cohort study finds that inducing therapeutic coma in patients with non-convulsive status epilepticus is linked to sharply higher rates of pneumonia, sepsis,...
Researchers have developed NN-IMODE, an improved multi-operator differential evolution algorithm that simultaneously optimizes the architecture and parameters of feedforward neural networks, achieving the best accuracy...
New research shows that fluorine-rich vapor from Finland's Wiborg rapakivi granite melted the Ihalainen marble deposit 1.6 billion years ago, producing an emulsion of silicate...
