• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Saturday, September 6, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

Noninvasive screening method reveals important properties of pharmaceutical tablets

Bioengineer by Bioengineer
January 10, 2017
in Science News
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Information on significant properties of pharmaceutical tablets, such as their mechanical strength and dissolution, can now be obtained without resorting to the conventional, time-consuming and destructive testing methods, according to a new study completed at the University of Eastern Finland. A new structural descriptive parameter based on terahertz (THz) time-domain techniques allow for a non-invasive detection of pharmaceutical tablet parameters, constituting a research breakthrough in the field of pharmacy.

The study focused on non-contact quality inspection of pharmaceutical tablets using terahertz time-domain techniques. Terahertz radiation represents the far end of the infrared band and it has unique properties that permit a quick and safe identification of pharmaceutical tablet properties. Using THz radiation, which is invisible and safe for human beings, it is possible to determine what a tablet is made of, including the nature of its constituents and how they are arranged. To this effect, the study has developed a novel structural descriptive parameter for pharmaceutical tablets, addressing the orientation of their microscopic structure. The parameter provides information on the pattern of arrangement of the various particulates as well as air pores within a tablet.

This fast and non-destructive screening method has significant applications in the inspection of the quality of individual tablets during production, providing information on the amount of active pharmaceutical ingredient, tablet porosity and weight, among other things. Another important application is that this method can detect counterfeit and substandard tablets (for example fake antimalarial tablets) flooding the markets in developing countries, where counterfeit drugs are a major cause of mortality.

The parameter constitutes a research breakthrough in the field of pharmacy, as in-depth understanding of its behaviour gives information on, e.g., the mechanical strength, content uniformity and dissolution of pharmaceutical tablets.

By utilising training sets of pharmaceutical tablets, scientists at the University of Eastern Finland in collaboration with scientists at the University of Cambridge, UK, and in Switzerland have successfully demonstrated the ability to non-invasively detect the porosity, weight and height of tablets. Based on these promising results, the researchers believe that an alternative non-destructive approach for quality screening of tablets can, in the future, replace the conventional destructive techniques such as mercury intrusion porosimetry. Hence, pharmacists and pharmaceutical scientists can now screen individual tablets even in the production line.

Since the majority (about 80%) of administered drugs are tablets, there is a significant need for a process analytical technology (PAT) tool that will permit the screening of individual pharmaceutical tablets before they reach end users. The methods were presented by Prince Bawuah, MSc, in his doctoral dissertation, and the findings were originally published in the International Journal of Pharmaceutics, European Journal of Pharmaceutics and Biopharmaceutics and Optical Review. The findings serve not only the pharmaceutical industry, but also pharmaceutical research.

###

The doctoral dissertation by Prince Bawuah, MSc, entitled Terahertz time-domain study on selected parameters of pharmaceutical tablets using effective medium approximation is available for download at: http://epublications.uef.fi/pub/urn_isbn_978-952-61-2311-0/urn_isbn_978-952-61-2311-0.pdf

For further information, please contact: Early-Stage Researcher Prince Bawuah, tel. +358 44 237 4671, [email protected]

Media Contact

Prince Bawuah
[email protected]
358-442-374-671
@UniEastFinland

http://www.uef.fi

############

Story Source: Materials provided by Scienmag

Share12Tweet8Share2ShareShareShare2

Related Posts

Phase II Study Finds Iza-Bren Plus Osimertinib Achieves 100% Response Rate in EGFR-Mutated NSCLC

September 6, 2025

Novel Antibody-Drug Conjugate Demonstrates Promising Efficacy in EGFR-Mutated NSCLC Patients

September 6, 2025

COMPEL Study Finds Adding Chemotherapy to Osimertinib After Progression Enhances Progression-Free Survival in EGFR-Mutated NSCLC

September 6, 2025

Sex Differences in Alcohol’s Impact on Brain Dopamine

September 6, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    150 shares
    Share 60 Tweet 38
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    116 shares
    Share 46 Tweet 29
  • First Confirmed Human Mpox Clade Ib Case China

    54 shares
    Share 22 Tweet 14

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Phase II Study Finds Iza-Bren Plus Osimertinib Achieves 100% Response Rate in EGFR-Mutated NSCLC

Novel Antibody-Drug Conjugate Demonstrates Promising Efficacy in EGFR-Mutated NSCLC Patients

COMPEL Study Finds Adding Chemotherapy to Osimertinib After Progression Enhances Progression-Free Survival in EGFR-Mutated NSCLC

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.