• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Thursday, September 25, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Neuroprosthesis Restores Grip in Stroke Patients

Bioengineer by Bioengineer
September 6, 2025
in Health
Reading Time: 3 mins read
0
Neuroprosthesis Restores Grip in Stroke Patients
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

A groundbreaking advancement in neuroprosthetics is set to transform rehabilitation for stroke survivors struggling with hand motor deficits. Researchers have unveiled a novel self-triggered grasp neuroprosthesis designed specifically to restore prehension functions in individuals with hemiparesis following a stroke. This innovative device leverages diverse control modalities to enable intuitive, real-time stimulation of finger extensor muscles, thereby facilitating grasping abilities that many patients have long lost despite traditional rehabilitation efforts.

Stroke remains the foremost cause of acquired motor impairments globally, leaving countless adults with compromised hand function. Recovery of active hand opening has proven particularly elusive for many, limiting their independence in daily activities. Addressing this gap, the newly developed grasp neuroprosthesis (GNP) prototype integrates self-triggering mechanisms attuned to the unique neuromuscular patterns of post-stroke individuals. The system’s adaptability aims not only to enhance usability but also to significantly improve real-world functional outcomes.

Deployment of the GNP was tested across two clinical research protocols involving 22 stroke survivors. Participants engaged with the device for multiple sessions over a week, during which they experienced nine distinct control modalities. Subjective evaluations focusing on ease-of-use and reliability revealed a strong preference for engaging the non-paretic foot as a triggering source—whether through EMG or IMU signals. Remarkably, both modalities received median ratings of 9 or 10 out of 10, underscoring their practicality and acceptance among users.

Functional impact was rigorously evaluated through standardized unimanual prehension tasks performed in a controlled, seated setting. Here, the GNP demonstrated a significant capacity to restore grasp capability, with improvements of up to three points on a five-point functional scale. This evidence supports the system’s real-world efficacy beyond laboratory metrics, suggesting meaningful gains in patients’ ability to perform everyday activities that require hand function.

The technology’s design focused not only on technical performance but also on ensuring practical deployment in the real lives of stroke survivors. By enabling users to select their preferred control modality from a versatile array of options, the neuroprosthesis accommodates individual differences in residual motor control and personal comfort. This user-centric approach could spur higher compliance and sustained use, essential factors in long-term rehabilitation success.

Another notable advancement lies in the device’s portability and envisaged home use. While the current prototype operates within a clinical setting, ongoing development efforts aim to create a wearable, self-contained version. Such iteration would facilitate continuous hand function support outside therapeutic environments, broadening the therapeutic reach and fostering patient autonomy in domestic contexts.

The study’s robust methodological framework—employing blinded evaluation, multi-crossover N-of-1 randomized controlled trials—adds credibility to the findings. The use of video analysis to assess functionality ensures objective, detailed appraisal of the neuroprosthesis’ impact on hand movements. This rigorous validation underscores the potential for clinical translation and widespread adoption.

Despite promising outcomes, challenges remain in ensuring seamless integration of the technology into diverse patient populations. Fine-tuning the algorithms to account for variability in user muscle activation patterns and motion signatures will be crucial. Moreover, user training protocols must be optimized to shorten acclimation periods while maximizing functional gains.

Envisioning future applications, this neuroprosthesis platform could inspire a new generation of adaptive assistive devices addressing various neuromotor impairments. Its modular control modalities and responsive stimulation strategies provide a versatile blueprint for restoring voluntary movements in patient groups beyond post-stroke populations, including those with spinal cord injuries or neurodegenerative diseases.

In conclusion, the development of this self-triggered grasp neuroprosthesis represents a significant leap toward practical, user-friendly restoration of hand function after stroke. Through advanced sensor integration, rapid responsiveness, and demonstrable functional improvements, the device holds promise to redefine rehabilitation paradigms. Continued innovation aimed at wearable deployment and personalized control strategies may soon enable stroke survivors to reclaim critical aspects of their independence and quality of life.

Subject of Research: Development and functional evaluation of a self-triggered grasp neuroprosthesis for restoring prehension in hemiparetic post-stroke individuals

Article Title: Specifications and functional impact of a self-triggered grasp neuroprosthesis developed to restore prehension in hemiparetic post-stroke subjects

Article References:
Le Guillou, R., Froger, J., Morin, M. et al. Specifications and functional impact of a self-triggered grasp neuroprosthesis developed to restore prehension in hemiparetic post-stroke subjects. BioMed Eng OnLine 23, 129 (2024). https://doi.org/10.1186/s12938-024-01323-y

Image Credits: AI Generated

DOI: https://doi.org/10.1186/s12938-024-01323-y

Tags: adaptive technology for stroke survivorsadvancements in neurorehabilitationgrasp neuroprosthesis technologyhemiparesis recovery devicesimproving independence in daily activitiesinnovative rehabilitation solutions for hand deficitsintuitive control of prosthetic limbsNeuroPrehens software for prostheticsneuroprosthesis for stroke rehabilitationovercoming motor impairments from strokereal-time muscle stimulation for graspingrestoring hand function after stroke

Share12Tweet8Share2ShareShareShare2

Related Posts

How Research Funding Drives the Development of Life-Changing Medicines

September 25, 2025

PinX1 Silencing Boosts Radiotherapy Efficacy in Lung Cancer

September 25, 2025

Carnosine and Beta-Alanine: Diabetes Supplementation Review

September 25, 2025

Building Effective Learning Health Systems: Key Strategies

September 25, 2025

POPULAR NEWS

  • New Study Reveals the Science Behind Exercise and Weight Loss

    New Study Reveals the Science Behind Exercise and Weight Loss

    76 shares
    Share 30 Tweet 19
  • Physicists Develop Visible Time Crystal for the First Time

    71 shares
    Share 28 Tweet 18
  • Scientists Discover and Synthesize Active Compound in Magic Mushrooms Again

    53 shares
    Share 21 Tweet 13
  • Tailored Gene-Editing Technology Emerges as a Promising Treatment for Fatal Pediatric Diseases

    51 shares
    Share 20 Tweet 13

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Color-changing strategies enhance prey protection according to environmental conditions

Engineered Bridge Recombinases Revolutionize Programmable DNA Rearrangements in Human Cells

Exploring Cooperation: New Study Shows How Mice and AI Work Together

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.