• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Thursday, October 2, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Health

Mount Sinai Study Reveals How Sex-Based Pelvic Differences Impact Spinal Screw and Rod Placement in Surgery

Bioengineer by Bioengineer
October 2, 2025
in Health
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Mount Sinai Researchers Uncover Critical Sex-Based Pelvic Variations Influencing Spinal Fixation Techniques

In a groundbreaking study published in Spine Deformity, the Mount Sinai Health System has revealed pivotal sex-based anatomical differences in pelvic morphology that profoundly impact the placement of spinal hardware during adult spinal deformity surgeries. This research elucidates how the divergent pelvic structures in men and women affect S2 alar-iliac (S2AI) screw positioning and lumbosacral rod alignment, highlighting the necessity for personalized surgical strategies tailored to each patient’s unique anatomy.

The pelvis, serving as a cornerstone for spinal fixation, exhibits significant morphological variation between sexes, historically acknowledged but rarely quantified with surgical precision. The latest insights from Mount Sinai demonstrate that men typically possess a narrower pelvic anatomy, resulting in a more medial starting position for S2AI screws. This subtle anatomical nuance drives clinically relevant challenges in achieving optimal rod alignment, a crucial factor for mechanical integrity and postoperative outcomes in spinal fusion procedures.

Technically, S2AI screws anchor the spinal construct to the pelvis, providing enhanced stability across the lumbosacral junction. Misalignment here can precipitate complications ranging from hardware failure to increased surgical times due to difficulties in rod contouring and fitting. The Mount Sinai team’s retrospective cohort analysis, comprising 185 cases from a single institution and involving multiple experienced surgeons, meticulously assessed postoperative radiographs and computed tomography scans to quantify these sex-related discrepancies.

Data revealed that male patients exhibited a significantly reduced distance between the posterior superior iliac spines (PSIS), averaging 7.1 cm compared to 8.1 cm in females. This constricted pelvic anatomy in men prompted a medialized screw entry point, which consequently forced rods to converge medially rather than maintain the ideal parallel orientation. Such malalignment necessitates enhanced rod bending intraoperatively, potentially compromising construct biomechanics and prolonging operative duration.

Further compounding these findings, the angular deviation of implant rods distally was markedly different between sexes. In males, rods showed an average convergence of −12.3 degrees, while females exhibited a divergence of +7.6 degrees, underscoring a pronounced divergence in spinal hardware alignment correlated with pelvic morphology. This novel quantification bridges a critical knowledge gap in spinal surgery, providing objective metrics to guide preoperative planning.

Clinically, these revelations bear profound implications. Surgeons must now anticipate sex-specific anatomical challenges when strategizing screw trajectories and fixation methods. The study advocates incorporating advanced intraoperative technologies such as navigation and robotics to mitigate alignment obstacles and reduce the need for excessive rod contouring. These adaptations promise to streamline complex procedures, decrease hardware-related complications, and ultimately enhance patient outcomes.

Mount Sinai’s research team underscores the study’s uniqueness, marking the first comprehensive effort to systematically characterize sex-based pelvic influences on S2AI screw placement and lumbosacral rod alignment within an adult deformity population. This pioneering work sets a critical precedent for future investigations, including biomechanical modeling and prospective clinical trials aimed at validating personalized surgical approaches.

The implications extend beyond technical refinements. In the era of precision medicine, understanding intrinsic anatomical variations enables the formulation of individualized surgical roadmaps, optimizing construct stability and patient recovery trajectories. This tailored approach exemplifies a paradigm shift toward integrating anatomical nuances with technological advancements in spine surgery.

Looking forward, the Mount Sinai researchers emphasize the need to evaluate whether these anatomical and biomechanical distinctions translate into measurable variations in long-term clinical outcomes such as implant longevity, rates of pseudarthrosis, and patient-reported quality of life indices. Such insights could revolutionize criteria for surgical candidacy and postoperative care algorithms.

Dr. James D. Lin, MD, MS, the study’s senior author, highlights, “Recognizing the anatomical diversity that underlies male and female pelvises compels us to rethink standardized approaches in spinal fixation. Our findings confirm that sex-specific strategies are not merely beneficial but necessary to elevate surgical precision and efficacy.” He further acknowledges contributions from Mount Sinai’s dedicated trainees, whose involvement was pivotal to this impactful discovery.

Mount Sinai Health System continues to be at the forefront of innovative healthcare solutions, marrying cutting-edge research with clinical excellence. This study exemplifies the institution’s commitment to advancing surgical science and enhancing individualized patient care, reinforcing Mount Sinai’s position as a leader in spinal deformity treatment.

As spinal surgery evolves, integrating comprehensive anatomical assessments with evolving technology will be essential. The insights derived from this seminal study provide a concrete foundation for transforming surgical paradigms, emphasizing the critical role of sex-specific pelvic anatomy in shaping successful spine surgery outcomes.

Subject of Research: Impact of sex-based pelvic anatomical differences on S2 alar-iliac screw positioning and lumbosacral rod alignment in adult spinal deformity surgery.

Article Title: Impact of sex on S2-alar-iliac pelvic screw position and lumbosacral rod alignment in adult spine deformity.

Web References: Spine Deformity Journal Article

Keywords: Orthopedics, Spine Surgery, Pelvic Anatomy, Sex Differences, S2 Alar-Iliac Screws, Spinal Deformity, Rod Alignment, Surgical Planning, Biomechanics, Personalized Medicine, Spinal Fusion, Adult Spine Surgery

Tags: Adult spinal deformity surgeryLumbosacral rod alignmentSex-based pelvic anatomySpinal screw placementSurgical planning
Share12Tweet8Share2ShareShareShare2

Related Posts

Barriers Facing Roma Women in Primary Healthcare

October 2, 2025
$3.7 Million NIH Grant Supports IU Research on ADHD Medication’s Impact on Substance Use in Youth

$3.7 Million NIH Grant Supports IU Research on ADHD Medication’s Impact on Substance Use in Youth

October 2, 2025

Ambient AI Scribes: A Breakthrough in Reducing Administrative Load and Combating Professional Burnout

October 2, 2025

Prolonged U.S. Residency Linked to Rising Heart Disease Risk Among Immigrants

October 2, 2025

POPULAR NEWS

  • New Study Reveals the Science Behind Exercise and Weight Loss

    New Study Reveals the Science Behind Exercise and Weight Loss

    91 shares
    Share 36 Tweet 23
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    78 shares
    Share 31 Tweet 20
  • Physicists Develop Visible Time Crystal for the First Time

    74 shares
    Share 30 Tweet 19
  • How Donor Human Milk Storage Impacts Gut Health in Preemies

    64 shares
    Share 26 Tweet 16

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Enhancing CAR T Cell Therapy for Solid Tumors

Tracking Raccoon Domestication Through Citizen Science Images

AI Composed Almost 25% of Corporate Press Releases in 2024

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 60 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.