• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Sunday, October 5, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

High fiber diets may alleviate inflammation caused by gout

Bioengineer by Bioengineer
January 4, 2017
in Science News
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

New research published in the Journal of Leukocyte Biology, shows that a high-fiber diet likely inhibits gout-related inflammation caused by monosodium urate (MSU) crystals. Specifically, researchers found that diets high in fiber trigger microorganisms in the gut to produce short chain fatty acids (SCFAs), which induce neutrophil apoptosis and the resolution of inflammation. These findings have important implications for the treatment of gout, and possibly for the treatment of arthritis.

"By understanding the way foods interact with living organisms, we may be able to create diets that help people with the disease, as well as their health overall," said Mauro M. Teixeira, Ph.D., a researcher involved in the work from the Immunopharmacology Group in the Department of Biochemistry and Immunology at the Institute of Biological Sciences at the Federal University of Minas Gerais in Minas Gerais, Brazil.

To make their discovery, scientists used a high-fiber diet and treatment with SCFAs to prevent inflammation associated with the injection of MSU crystals in the knees of mice. Kinetic experiments showed that this caused neutrophil apoptosis and efferocytosis. Resolution of inflammation also was accompanied by enhancement of the production of anti-inflammatory cytokines in the knee joint, further preventing knee damage and dysfunction.

"We are seeing an explosion in our mechanistic understanding of how microbial communities in our intestines and elsewhere influence multiple aspects of immune and metabolic health," said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology. "This work is an elegant example of how tuning of inflammatory circuits by linking diet to microbial products can have a profound effect on an inflammatory disease in the joints. Future work may allow such findings to be translated into practical treatments for gout and other diseases."

###

The Journal of Leukocyte Biology publishes peer-reviewed manuscripts on original investigations focusing on the cellular and molecular biology of leukocytes and on the origins, the developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes and other cells involved in host defense and inflammation.

Details: Angélica T. Vieira, Izabela Galvão, Laurence M. Macia, Érica M. Sernaglia, Marco Aurélio R. Vinolo, Cristiana C. Garcia, Luciana P. Tavares, Flávio A. Amaral, Lirlândia P. Sousa, Flaviano S. Martins, Charles R. Mackay, and Mauro M. Teixeira. Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice. J. Leukoc. Biol. January 2017 101:275-284; doi:10.1189/jlb.3A1015-453RRR ; http://www.jleukbio.org/content/101/1/275.abstract

Media Contact

Cody Mooneyhan
[email protected]
301-634-7104
@fasebopa

http://www.faseb.org

############

Story Source: Materials provided by Scienmag

Share12Tweet8Share2ShareShareShare2

Related Posts

Empowering Older Adults: Shared Decision-Making in Nursing

October 5, 2025
blank

Whole Genome Analysis Uncovers Variations in Goat Pigmentation

October 5, 2025

Boosting Malonylation Site Detection with AlphaFold2

October 5, 2025

Assessing Drug Interactions in Neonatal Care Software

October 5, 2025
Please login to join discussion

POPULAR NEWS

  • New Study Reveals the Science Behind Exercise and Weight Loss

    New Study Reveals the Science Behind Exercise and Weight Loss

    94 shares
    Share 38 Tweet 24
  • New Study Indicates Children’s Risk of Long COVID Could Double Following a Second Infection – The Lancet Infectious Diseases

    92 shares
    Share 37 Tweet 23
  • Physicists Develop Visible Time Crystal for the First Time

    75 shares
    Share 30 Tweet 19
  • New Insights Suggest ALS May Be an Autoimmune Disease

    71 shares
    Share 28 Tweet 18

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Empowering Older Adults: Shared Decision-Making in Nursing

Whole Genome Analysis Uncovers Variations in Goat Pigmentation

Boosting Malonylation Site Detection with AlphaFold2

Subscribe to Blog via Email

Success! An email was just sent to confirm your subscription. Please find the email now and click 'Confirm' to start subscribing.

Join 62 other subscribers
  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.