• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Thursday, September 4, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News

Genome sequenced for pesky pumpkin pathogen

Bioengineer by Bioengineer
March 24, 2021
in Science News
Reading Time: 3 mins read
0
IMAGE
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Montgomery Flack

URBANA, Ill. – Pumpkin growers dread the tiny tan scabs that form on their fruit, each lesion a telltale sign of bacterial spot disease. The specks don’t just mar the fruit’s flesh, they provide entry points for rot-inducing fungus and other pathogens that can destroy pumpkins and other cucurbits from the inside out. Either way, farmers pay the price, with marketable yields reduced by as much as 90%.

Despite the disease’s severity, scientists don’t know much about the genetics of the pathogen that causes it; nearly all the molecular information required for accurate diagnostic testing and targeted treatments is lacking for the disease.

In a new study, University of Illinois scientists, with the help of two undergraduate students, have assembled the first complete genome for the bacteria that causes the disease, Xanthomonas cucurbitae, and identified genes that are activated during infection.

“Assembling a complete circular genome means we now have the resources to better understand what’s happening in the field. We can use this information to look at how the pathogen is spreading, whether there are differences in host specificity among sub-populations or strains, or how likely it is to develop resistance to chemical controls,” says Sarah Hind, assistant professor in the Department of Crop Sciences at Illinois and senior author on the Phytopathology study.

After sequencing the genome, Hind’s group compared it to genomes from 12 other Xanthomonas species that cause diseases in a variety of crop plants like tomato, rice, citrus, and wheat. Surprisingly, given its penchant for creating havoc in the field, Xanthomonas cucurbitae had the smallest genome and had fewer genes known to be important for other Xanthomonas species to cause disease.

“As this pathogen lacks many of the known virulence (i.e., disease-causing) genes, we don’t know exactly which genes are needed by the pathogen to infect cucurbit plants,” Hind says. “It could be something we’ve never seen before, such as a new gene or a mechanism that evolved in this species that isn’t seen in the rest of the family. That could be very exciting.”

To get closer to an answer, the research team grew the bacteria in liquid media that mimicked its host environment and identified more than 400 genes whose expression was altered when the pathogen interacted with its “host.” In particular, they observed increased expression of genes for enzymes related to the breakdown of plant tissues, which are key for further development of the disease.

If Hind’s team can learn more about these factors and how cucurbits respond to them, there may be a way to prevent the bacteria from penetrating pumpkin fruits in the first place. “That would really save the farmers,” she says. “They don’t care as much when it gets on the leaves, but if it infects the fruit, they’re in trouble.”

Hind adds, “This project wouldn’t have been possible without the contributions of some really talented undergraduate students. We love having students participate in our research. They bring a sense of enthusiasm and eagerness – as well as really creative ideas – to the lab that would be hard to generate otherwise.”

Although both students graduated, see new Crop Sciences students contributing to Hind’s other pumpkin projects in this video. High school and transfer students can learn more about Crop Sciences coursework online.

###

The article, “Genome sequencing and functional characterization of Xanthomonas cucurbitae, the causal agent of bacterial spot disease of cucurbits,” is published in Phytopathology [DOI: 10.1094/PHYTO-06-20-0228-R]. Authors include Rikky Rai, Julius Pasion, Tanvi Majumdar, Cory Green, and Sarah Hind. The research was supported with USDA Hatch funds, as well as an ACES Undergraduate Research Scholarship to Tanvi Majumdar.

The Department of Crop Sciences is in the College of Agricultural, Consumer and Environmental Sciences at the University of Illinois at Urbana-Champaign.

Media Contact
Lauren Quinn
[email protected]

Original Source

https://aces.illinois.edu/news/genome-sequenced-pesky-pumpkin-pathogen

Related Journal Article

http://dx.doi.org/10.1094/PHYTO-06-20-0228-R

Tags: Agricultural Production/EconomicsAgricultureBacteriologyBiologyFertilizers/Pest ManagementGenesGeneticsMicrobiologyPlant Sciences
Share12Tweet8Share2ShareShareShare2

Related Posts

Baby Food Claims Don’t Hold Up, Study Finds

September 4, 2025

Scientists Identify Crucial Human Proteins Driving Coronavirus Replication, Unveiling Promising Targets for New Therapies

September 4, 2025

Bio-Oil Derived from Corn Stalks and Wood Debris Offers Promising Solution for Plugging Orphaned Fossil Fuel Wells

September 4, 2025

Needlestick Injury Rates in Nurses and Students in Pakistan

September 4, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    149 shares
    Share 60 Tweet 37
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    115 shares
    Share 46 Tweet 29
  • Modified DASH Diet Reduces Blood Sugar Levels in Adults with Type 2 Diabetes, Clinical Trial Finds

    61 shares
    Share 24 Tweet 15

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Baby Food Claims Don’t Hold Up, Study Finds

Scientists Identify Crucial Human Proteins Driving Coronavirus Replication, Unveiling Promising Targets for New Therapies

Bio-Oil Derived from Corn Stalks and Wood Debris Offers Promising Solution for Plugging Orphaned Fossil Fuel Wells

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.