Science News
Proteomics and machine learning identify biomarkers in heart attack-related cardiogenic shock
Acute myocardial infarction complicated by cardiogenic shock remains one of the most dangerous emergencies in modern cardiovascular medicine. Even when...
Scientists Create Polycaprolactone-Based 2D Platelets Through Living Crystallization-Driven Self-Assembly
A new polymer-assembly protocol is turning a familiar biodegradable polyester into precisely shaped two-dimensional nanomaterials. In a study published in...
Noncircadian BMAL1–YAP signaling amplifies chronic inflammation in aging skin
Aging Skin’s Molecular Switch: Noncircadian BMAL1–YAP Cooperation Amplifies Chronic Inflammation Aging skin is often described as a visible record of...
Iron-driven ferroptosis weakens CAR-T cell function and antitumor effectiveness
Chimeric antigen receptor T-cell therapy has transformed the treatment of several blood cancers, yet its success often depends on how...
Alpha protein kinase 3 gene therapy restores heart function in cardiomyopathy models
A gene therapy designed to replace a damaged or missing copy of the alpha protein kinase 3 gene has restored...
Copper Catalyst Directly Converts Aliphatic Primary Amines into Nitriles Through Deaminative Cyanation
A simple chemical transformation could give ordinary aliphatic amines a remarkable new identity: the ability to become nitriles in a...
Balanced mRNA and ribosome levels govern growth in eukaryotic cells
A new study in budding yeast suggests that one of biology’s most fundamental processes—cell growth—may be governed by a remarkably...
Non-native plants’ mycorrhizal strategies shift across biomes and disturbance levels
A global study has challenged one of ecology’s most persistent assumptions about invasive plants: that their success is consistently powered...
Japanese Colorectal Cancer Reveals Prevalence, Timing, and Microbiome Signatures of Colibactin Mutations
Colorectal cancer is often described as a disease written into the genome, but the authors of a new study argue...
Smoking and Lower Education Linked to Excess Premature Deaths in U.S.
Smoking and limited access to education appear to be combining into a powerful, preventable driver of premature death in the...
New CAF Population Directs Highly Suppressive Regulatory T Cells in Lung Tumors
A previously unrecognized population of cancer-associated fibroblasts appears to act as a spatial organizer for immune suppression in lung cancer,...
Deep Learning-Enhanced Bimodal Sensor Enables Intelligent Recognition and Navigation
A new flexible sensor could help machines see, feel and make decisions with a level of coordination that has long...
Flux-driven ligand exchange reshapes metal–organic framework glasses
Metal–organic frameworks, or MOFs, are best known as highly ordered crystalline materials whose molecular building blocks assemble into repeating networks...
Oral Nanodelivery of Gut Microbial Metabolite Boosts T-Cell Stemness in Cancer Immunotherapy
Han, Cho, Takahashi and colleagues have reported a potential new way to strengthen cancer immunotherapy from inside the gut: an...
Protein nanocrates overcome air–water interface artifacts in cryo-EM
Cryo-electron microscopy has transformed structural biology by allowing scientists to visualize proteins and other biological machines at near-atomic resolution. Yet...
In-place dry repair and passivation deliver size-independent performance in III-nitride micro-LEDs
Micro-LEDs have long promised to transform displays for smartphones, televisions, smart glasses and immersive virtual-reality headsets, combining extraordinary brightness with...
Spectroscopy Reveals Wigner Crystal Polarons in Atomically Thin Semiconductor
A new study has brought physicists closer to watching an exotic state of matter reveal itself through light. In research...
Nucleosomes and IDRs Restrain GCN4’s Promiscuous Binding on Minichromosomes
A new study is reshaping the way scientists understand how transcription factors find their targets inside the crowded genome. Researchers...
Multifunctional phosphine enables selective orthogonal hydrogenation of alkenes
A new strategy for one of organic chemistry’s most persistent selectivity problems could give chemists a more precise way to...
Generative AI’s STEM Learning Impact and Limits Revealed by Systematic Review
Generative artificial intelligence may be transforming STEM education—but not in the simple, universally positive way suggested by many early headlines....