Science News
Untangling chromosomal and hormonal effects to make sex-specific endothelial OCT4 clinically actionable
The vascular biology community has just been handed both a discovery and a warning in a single package. In a...
Waldenström’s macroglobulinemia in siblings: 25 years of institutional cases reviewed
In medicine’s long catalogue of rare events, few sights arrest a hematologist like the same cancer surfacing twice within a...
Disrupting CDK4/6–RARα–NF-κB axis eases senescence inflammation, improving aging and chemotherapy recovery
A drug that millions of people with breast cancer already take every day may be hiding a second, unexpected talent:...
NPTN gene variants linked to autism through disrupted brain cell signaling
Scientists have identified a new genetic cause of autism and intellectual disability — and traced it to an unexpected place:...
BEGONIA trial: durvalumab plus trastuzumab deruxtecan for HER2-low metastatic breast cancer
In one of oncology’s most closely watched experiments, an antibody-drug conjugate paired with an immune checkpoint inhibitor has produced unusually...
AI-powered eye scans reveal links to heart and brain health
A routine photograph of the back of the eye has quietly become one of the most information-dense objects in modern...
Fertility benefits may explain why harmful disease genes persist in humans
One of the oldest puzzles in evolutionary biology has just received what may be its most complete genomic answer: why...
Round-robin tests quantify catalyst activity and deactivation in CO2 hydrogenation modelling
In the race to harness artificial intelligence for discovering better catalysts, a sobering new study has emerged that quantifies just...
New atlas reveals mesenchymal diversity in human gut and organoids
Beneath every square centimeter of the human small intestine lies a hidden scaffold of cells that has quietly governed one...
New spatial transcriptomics method maps RNA isoforms across primate brain cells
For two decades, neuroscientists have been building ever finer maps of gene activity in the brain, charting which genes switch...
Transcription factors steer distinct pancreatic cancer cell states and drug dependencies
Pancreatic cancer has earned its grim reputation the hard way. Fewer than one in eight patients survives five years beyond...
Lewis acids turn degradation into useful doping for organic semiconductors
For decades, chemists working on electronic materials have treated molecular decomposition as the enemy—a process to be suppressed with every...
Tuberculosis interventions deliver major global impact at affordable cost
Tuberculosis has quietly reclaimed a title no pathogen should want: the world’s deadliest infectious disease. According to the World Health...
Gut microbiome imbalance expands inflammatory dendritic cells, triggering early autoimmunity
Long before lupus announces itself with swollen joints and damaged kidneys, long before type 1 diabetes destroys enough insulin-producing cells...
Nanoscale imaging reveals magnetic brightening of spin-polarized helical edge modes in ZrTe5
Physicists have, for the first time, directly imaged the exotic edge currents that race along the boundary of zirconium pentatelluride,...
Tuning 2D perovskites yields efficient, stable perovskite-silicon tandem solar cells
Researchers have engineered a molecular-level solution to one of the most stubborn efficiency bottlenecks in perovskite solar technology, achieving a...
Quantum Hall antidot acts as a fractional charge meter
Physicists have demonstrated a new type of extremely sensitive charge detector built on the quantum Hall effect, capable of resolving...
Portable SERS sensor measures full-range underwater pH directly in the field
Few measurements seem as straightforward as dipping a probe into water and reading its pH. Fewer still survive intact where...
Human TOM and TIM22 complexes join forces to import mitochondrial carriers
You are the science news desk of a major English-language science magazine. Complete the task immediately. Never ask the reader...
Researchers reveal guiding principles for electrochemical synthesis of multimetallic nanocrystals
For much of the past three decades, coaxing nanocrystals made of more than one metal into existence has been closer...