• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Saturday, August 30, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Biology

Cardiac arrhythmias linked to gene mutations

Bioengineer by Bioengineer
September 29, 2020
in Biology
Reading Time: 2 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

IMAGE

Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, September 28, 2020—Life-threatening cardiac arrhythmias can be linked to the functional and structural consequences of gene mutations. The study is published in the peer-reviewed journal Bioelectricity. Click here to read the full-text article free on the Bioelectricity website through October 28, 2020.

“Voltage-gated sodium (Nav) channel activity in the heart enables us to live! In enabling this, the channel proteins associate with auxiliary (‘ß’) subunits. Now we see how important the ß-subunit integrity is to heart function,” says Co-Editor-in-Chief Mustafa Djamgoz, PhD, Imperial College London.

The researchers used X-ray crystallography and electrophysiological measurements. They examined the interaction of voltage-gated sodium (Nav) channels with cardiac arrhythmia-associated mutations in SCN2B (or ß2) and SCN4B (or ß4) genes that are known generally to modify Nav channel function. 

“SCN4B180T data suggested a functionally important region in the interaction between Nav1.5 and ß4 that, when disrupted, could lead to thermal instability and channel dysfunction,” state Filip Van Petegem, PhD, University of British Columbia, Frank Bosmans, PhD, Ghent University, and coauthors.

“Ion channels are critical for many functions in the body. The improved understanding of how genetic sequence contributes to bioelectric properties in cells will provide insight into not only cardiac syndromes but also cancer, birth defects, and organ repair,” says Co-Editor-in-Chief Michael Levin, PhD, Tufts University. 

###

About the Journal
Bioelectricity is the only peer-reviewed journal dedicated to the study of the natural electricity within living organisms and how to harness this phenomenon to treat and cure disease. The Journal, led by Co-Editors-in-Chief Mustafa Djamgoz, PhD, Imperial College London, and Michael Levin, PhD, Tufts University, publishes groundbreaking multidisciplinary research and advances documenting this next step in the evolution of how we study life. For complete tables of content and a sample issue, please visit the  Bioelectricity website.

About the Publisher
Mary Ann Liebert, Inc., publishers is known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s 90 journals, newsmagazines, and books is available on the Mary Ann Liebert, Inc., publishers website.

Media Contact
Kathryn Ryan
[email protected]

Original Source

https://home.liebertpub.com/news/cardiac-arrhythmias-linked-to-gene-mutations/3757

Related Journal Article

http://dx.doi.org/10.1089/bioe.2020.0030

Tags: BiologyCell BiologyClinical TrialsGene Therapy
Share12Tweet8Share2ShareShareShare2

Related Posts

Impact of Environment on Hornbill Behavior in Zoos

August 30, 2025

circ_0020850: Key Indicator for Stroke Recovery

August 30, 2025

Examining DnaJ Gene Family’s Response to Salt Stress

August 30, 2025

New Single-Cell Atlas Unveils Starlet Anemone Secrets

August 30, 2025
Please login to join discussion

POPULAR NEWS

  • blank

    Breakthrough in Computer Hardware Advances Solves Complex Optimization Challenges

    151 shares
    Share 60 Tweet 38
  • Molecules in Focus: Capturing the Timeless Dance of Particles

    142 shares
    Share 57 Tweet 36
  • New Drug Formulation Transforms Intravenous Treatments into Rapid Injections

    116 shares
    Share 46 Tweet 29
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    82 shares
    Share 33 Tweet 21

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

JARID2 Variant Linked to Female Infertility Issues

Mitochondrial ADP-Ribosylation Controls Heart Sepsis Response

Unveiling PIPC: Risks of Inappropriate Prescription Cascades

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.