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Home NEWS Science News

Biologists find missing link for the ‘safe’ signal in plants

Bioengineer by Bioengineer
May 30, 2017
in Science News
Reading Time: 3 mins read
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The hormone jasmonic acid plays a major role in the plant immune system and in regulating growth. Scientists have already learned much about how jasmonic acid works, but one important link was missing: what makes the plant's jasmonic acid level go down once the attack by a fungus or insect has been warded off? Plant biologists at Utrecht University and colleagues from the University of Amsterdam, have now discovered how the plant metabolises jasmonic acid, issuing the signal 'safe'. Controlling this mechanism may present new opportunities to increase resistance of crops to fungi and insects. The results of their research were published in the scientific journal PNAS on Tuesday 30 May.

Once a plant detects an insect or fungus, it begins to produce the hormone jasmonic acid, which initiates an immune response that prevents further damage. After the attack, jasmonic acid is quickly broken down again. This is necessary because the hormone inhibits plant growth and development.

Four enzymes

Until now, scientists did not know how jasmonic acid is broken down in the plant. But in their research on the model plant Arabidopsis thaliana, biologists at Utrecht University and the University of Amsterdam have discovered that four related enzymes have this activity.

Missing link

Each of these four enzymes can perform a chemical reaction in which an oxygen atom is added to jasmonic acid. This creates an inactive variant of the hormone, 12-hydroxy-jasmonic acid. While high concentrations of jasmonic acid activate the plant's immune system, this does not occur with the inactive variant. With this discovery, the scientists have found an important missing link as to how the plant controls its levels of jasmonic acid.

Increasing resistance

"Now that we know about these enzymes, we have the opportunity to control the concentration of jasmonic acid in order to increase the plant's resistance", explains research leader Prof. Guido Van den Ackerveken from Utrecht University. "Our research shows that plants are much more resistant to insects and pathogenic fungi if we turn off the four enzymes in a plant. One major disadvantage to this, however, is that it inhibits the plant's growth and development. So the trick is to find the right balance.".

###

Publication

'Arabidopsis JASMONATE-INDUCED OXYGENASES down-regulate plant immunity by hydroxylation and inactivation of the hormone jasmonic acid'

Lotte Caarls*, Joyce Elberse*, Mo Awwanah*, Nora R. Ludwig*, Michel de Vries, Tieme Zeilmaker*, Saskia C.M. Van Wees*, Robert C. Schuurink, and Guido Van den Ackerveken*

PNAS, doi, 30 May 2017

* affiliated with Utrecht University

Image and photo caption

1. Photo from the publication: left a 'normal' plant with a fungal infection, right a plant in which the enzymes have been switched off. By switching off the enzymes, the plant on the right has increased resistance to the fungus, and therefore displays less disease symptoms. But it clearly also has consequences for the plant's growth and development.

2. Arabidopsis with caterpillar, credits Hans van Pelt, Utrecht University.

More information

Research group: https://www.uu.nl/en/research/plant-microbe-interactions/guido-van-den-ackerveken

This research was part of Utrecht University's interdisciplinary research theme Future Food. Future Food Utrecht combines the efforts of botanists, cell biologists, pharmaceutical researchers, social scientists, urban geographers, medical and veterinary researchers, ethicists and economists from Utrecht University and UMC Utrecht.

More information: https://www.uu.nl/en/research/future-food-utrecht

Contact

Monica van der Garde, Public Information Officer, Faculty of Science Utrecht University: [email protected], + 31 (0)6 13 66 14 38.

Media Contact

Monica van der Garde
[email protected]
31-613-661-438

http://www.uu.nl

############

Story Source: Materials provided by Scienmag

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