At the Nicolelis Laboratory at Duke University, Miguel Nicolelis is best known for pioneering studies in neuronal population coding, Brain Machine Interfaces (BMI) and neuroprosthetics in human patients and non-human primates. But his lab has also developed an integrative approach to studying neurological and psychiatric disorders including Parkinsons disease and epilepsy. The approach, they hope, will allow the integration of molecular, cellular, systems, and behavioral data in the same animal, producing a more complete understanding of the nature of the neurophysiological alterations associated with these disorders.