NEW YORK (October 5, 2018) — During a nationwide outbreak of healthcare-associated infections of an antibiotic-resistant bacteria, an Israeli hospital traced repeated infections of patients in its intensive care unit (ICU) to an unexpected source–sink traps, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.
"Understanding the source of these resistant bacteria and how they were being spread was essential to effectively intervening and preventing the further spread," said Gili Regev-Yochay, MD, lead author of the study and Director of the Infection Prevention & Control Unit at Sheba Medical Center at Tel HaShomer in Israel. "While we were unable to prevent the sink traps from being colonized, by changing our behavior associated with the sinks we have prevented the spread of these infections."
From January 2016 to May 2017, 32 cases of OXA-48 Carbapenemase-producing Enterobacteriaceae (CPE) were detected, with all but the first two traced to the same bacteria. Most cases were initially detected through routine screening, 11 developed clinical infections, and three deaths were directly attributed to these infections.
The infection control team work closely with staff from the ICU–including clinicians, cleaning staff, a pharmacist and social worker–to systematically trace the source of CPE contamination to 22 sinks in the 16-bed ICU. Frequent decontamination of the sinks using different techniques only temporarily eliminated bacteria. However, decontamination combined with the adoption of sink contamination prevention guidelines eliminated new infections.
CPE is usually spread from one patient to another through contact with staff or objects moved from room to room. But increasingly, hospital water has been recognized as a source of carbapenem-resistant organisms, the authors said. Running water from a sink can create an aerosol contamination of bacteria that can spread at least a meter from the sink during handwashing, authors said. Effective guidelines used by researchers included limited use of sinks in patient rooms, only using sinks for hand washing when necessary, a ban on clinical waste disposal in sinks, and avoiding storage of materials near the sinks.
Initial sink decontamination efforts included routine cleaning with bleach and later with acetic-acid, but weekly sampling showed that these efforts were effective for only a short time. In one room with a contaminated sink, a self-disinfecting sink trap was installed, but the trap was removed after a patient in a neighboring room acquired an infection from the same bacteria that was detected again in the new trap.
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Gili Regev-Yochay, MD, MS; Gill Smollen, MD; Ilana Tal, RN; Nani Pinas Zade, RN; Yael Haviv, MD, Valery Nudelman, RN; Ohad Gal-Mor, PhD; Hanaa Jaber, BsC;, Eyal Zimlichman, MD; Nati Keller, MD, and Galia Rahav, MD. "Sink-traps as the Source of Transmission of Serratia marcescens-OXA48 in an Intensive Care Unit" Web (October 4, 2018).
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Published through a partnership between the Society for Healthcare Epidemiology of America and Cambridge University Press, Infection Control & Hospital Epidemiology provides original, peer reviewed scientific articles for anyone involved with an infection control or epidemiology program in a hospital or healthcare facility. ICHE is ranked 19th out of 83 Infectious Disease Journals in the latest Web of Knowledge Journal Citation Reports from Thomson Reuters.
The Society for Healthcare Epidemiology of America (SHEA) is a professional society representing more than 2,000 physicians and other healthcare professionals around the world who possess expertise and passion for healthcare epidemiology, infection prevention, and antimicrobial stewardship. The society's work improves public health by establishing infection-prevention measures and supporting antibiotic stewardship among healthcare providers, hospitals, and health systems. This is accomplished by leading research studies, translating research into clinical practice, developing evidence-based policies, optimizing antibiotic stewardship, and advancing the field of healthcare epidemiology. SHEA and its members strive to improve patient outcomes and create a safer, healthier future for all. Visit SHEA online at http://www.shea-online.org, http://www.facebook.com/SHEApreventingHAIs and @SHEA_Epi.
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http://dx.doi.org/10.1017/ice.2018.235
