University of Liverpool researchers have identified that hospital admissions in England for ectopic pregnancy (when a fertilised egg implants outside the womb) have been increasing since 2021, with more than twice as many admissions of women from most deprived areas than the least deprived areas.
Ectopic pregnancy is one of the most common early pregnancy complications with an estimated 11,000 hospital admissions annually – around 1 in every 90 pregnancies. Sadly, ectopic pregnancies result in pregnancy loss and can be a risk to the mother’s health if the pregnancy continues.
Published in The Lancet Regional Health – Europe, the paper outlines the first 20-year national analysis of NHS England data on this topic.
Analysing hospital and maternity services data from 2004 to 2024, the researchers identified that ectopic pregnancy admissions rose significantly from 2004 to 2012 with an average increase of roughly 3% each year, stabilised between 2012 and 2021, then rose again significantly after 2021 with an average increase of over 4% each year.
Authors suggest this increase may reflect demographic changes such as rising maternal age, increased rates of risk factors such as obesity, and disruption to hospitals and maternity services due to the COVID-19 pandemic.
Dr Nicola Tempest, Academic Clinical Lecturer, from the University’s Department of Women’s and Children’s Health said: “Pregnancy loss affects millions of women worldwide, yet we know surprisingly little about how its prevalence and impact has changed over time.
“Our research shows that admissions for ectopic pregnancy have continued to rise despite declining birth rates, highlighting an ongoing demand for NHS services.
“Women from the most deprived areas consistently experienced much higher admission rates for both miscarriage and ectopic pregnancy, underlining persistent health inequalities.
“Pregnancy loss should be recognised as a major women’s health research priority so we can better understand its causes and develop services that meet women’s needs and address the risk factors that are contributing to these rates.
“Importantly, research must address one of the most common and deeply personal questions women ask after pregnancy loss: “Why did this happen to me?”
The study also found that miscarriage admissions declined significantly between 2018 and 2021, with subsequent years showing a modest increase that did not reach statistical significance.
For more than a decade, women living in the most deprived communities faced over twice the rate of hospital admissions for miscarriage and ectopic pregnancy compared with those in the least deprived areas. The authors point to preventable inequalities in health, risk factors and access to care as likely contributors.
Dr Tempest concluded: “These findings show that where a woman lives continues to have a profound influence on her reproductive health outcomes. Ultimately, reducing these inequalities will require an equity-focused approach that combines high-quality clinical care with prevention, education and services designed around the needs of the communities most at risk.
“Behind every admission for pregnancy loss, there is a woman, a family and an unanswered question, our aim and mission is not only to improve the care but also to understand and prevent it.”
The paper, ‘Temporal and socioeconomic trends in hospital admissions for miscarriage and ectopic pregnancy in England, 2004–2024: a nationwide study’ was published in The Lancet Regional Health – Europe (DOI: 10.1016/j.lanepe.2026.101777).
NOTES TO EDITORS
About the University of Liverpool
Founded in 1881 as the original ‘red brick’, the University of Liverpool is one of the UK’s leading research-intensive higher education institutions with an annual turnover of £726.3 million, including an annual research income of £166.0 million.
Now ranked in the top 140 universities worldwide in the QS World Rankings 2027 and top 150 in the Times Higher Education World University Rankings 2026, we are a member of the prestigious Russell Group of the UK’s leading research universities and have a global reach and influence that reflects our academic heritage as one of the country’s largest civic institutions.
The latest UK rankings of circa 130 institutions have placed the University of Liverpool at 18th (Times and Sunday Times Good University Guide 2025), 22nd (2026 Guardian University Guide), 25th (Daily Mail University Guide 2025) and 23rd (2026 Complete University Guide) nationally.
Journal
The Lancet Regional Health – Europe
DOI
10.1016/j.lanepe.2026.101777
Method of Research
Observational study
Subject of Research
People
Article Title
Temporal and socioeconomic trends in hospital admissions for miscarriage and ectopic pregnancy in England, 2004–2024: a nationwide study
Article Publication Date
29-Jul-2026
Media Contact
Sarah Stamper
University of Liverpool
Cell: 07970247396
Journal
The Lancet Regional Health – Europe
DOI
10.1016/j.lanepe.2026.101777
Journal
The Lancet Regional Health – Europe
DOI
10.1016/j.lanepe.2026.101777
Method of Research
Observational study
Subject of Research
People
Article Title
Temporal and socioeconomic trends in hospital admissions for miscarriage and ectopic pregnancy in England, 2004–2024: a nationwide study
Article Publication Date
29-Jul-2026
Tags
/Health and medicine/Human health/Human biology/Human reproduction/Pregnancy
/Life sciences/Developmental biology/Reproductive biology
/Health and medicine/Human health/Human biology
/Health and medicine/Health care
