Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, including humans
Credit: Professor Tony Schountz, Colorado State University (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)
Bat influenza A viruses use MHC-II for cell entry; this study shows that highly conserved amino acids within MHC-II are key for infection and provide an explanation for the ability of these viruses to target MHC-II from a broad range of vertebrates, including humans
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In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002182
Article Title: Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells
Author Countries: Germany, Thailand, the Netherlands, United Kingdom
Funding: see manuscript
Journal
PLoS Biology
DOI
10.1371/journal.pbio.3002182
COI Statement
Competing interests: The authors have declared that no competing interests exist.
