ALDH2 Suppresses Multiple Myeloma Progression by Restraining the E2F Signaling Pathway
Researchers found that ALDH2 acts as an independent favorable prognostic biomarker in multiple myeloma, curbing cancer cell proliferation and promoting ...
Researchers found that ALDH2 acts as an independent favorable prognostic biomarker in multiple myeloma, curbing cancer cell proliferation and promoting ...
A real-world retrospective study demonstrates that adding first-line immunotherapy to chemotherapy significantly prolongs median overall survival by 23 months in ...
A systematic review and meta-analysis found that adding immune checkpoint inhibitors to chemotherapy significantly improves progression-free survival, but not overall ...
A multi-database and laboratory evaluation identifies immune checkpoint CD112 as an independent prognostic biomarker linked to reduced survival in cervical ...
A retrospective study shows that quantified baseline ascites volume above 613.5 milliliters independently predicts significantly reduced survival in patients receiving ...
A systematic review found no statistically significant correlation between preclinical rodent xenograft efficacy endpoints and phase II trial outcomes in ...
A SEER-based study of 1,660 patients with solitary plasmacytoma of the spine shows survival probabilities improve with each year survived ...
A clinical review indicates that rare hematologic immune-related adverse events from checkpoint inhibitors correlate with reduced disease recurrence and improved ...
A retrospective single-center study found that early brain radiotherapy combined with third-generation EGFR-TKIs was associated with significantly longer survival outcomes ...
A two-center retrospective cohort study reveals that cardiovascular comorbidity fundamentally alters the clinical indicators predicting survival following hospitalization for acute ...
A decision-tree simulation shows that pathologist-initiated reflex testing for non-small cell lung cancer improves survival while lowering annual healthcare expenditures ...
Integrative single-cell and transcriptomic analyses reveal that fibroblast-derived miR-486-3p suppresses bladder cancer progression by targeting the HER-2 oncogenic axis.
In an analysis of clinical tissue specimens and cell models, researchers identified that downregulated lncRNA TRHDE-AS1 independently predicts reduced overall ...
A retrospective cohort study demonstrates that baseline splenic volume of 315 cubic centimeters or greater independently predicts significantly shorter progression-free ...
A two-center retrospective study found similar survival rates between local excision and intersphincteric resection after neoadjuvant therapy for ultra-low rectal ...
Severe early thrombocytopenia following CAR T-cell therapy is associated with reduced overall survival and higher relapse rates in patients with ...
A retrospective cohort study of 230 patients with intermediate-stage hepatocellular carcinoma found that adding complete ablation to transarterial chemoembolization and ...
A structured review and institutional case series indicates that ovarian small-cell carcinoma of pulmonary type frequently presents at advanced stages ...
An integrated study of stomach adenocarcinoma found that NTN1 transcript levels were lower in tumors than normal tissues and correlated ...
A retrospective cohort study of 375 breast cancer patients found that pre-treatment cardiac calcium burden and radiation doses to the ...
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