Inside the Snake Gut: First Look at the Microbiome of a Himalayan Keelback
The first metagenomic and metabolomic survey of the orange-collared keelback reveals a shared core gut microbiome with segment-specific differences in ...
Tag: Metabolomics
New Drug Candidates Starve Cryptosporidium Parasites by Blocking Their Energy Supply
Researchers engineered 1,440 derivatives of an anti-Cryptosporidium compound and identified two potent lactate dehydrogenase inhibitors that clear the parasite in ...
Older Yaks Produce Milk With a Distinct Molecular Fingerprint, Multi-Omics Study Reveals
A multi-omics study finds that senior yaks produce milk with distinct age-related signatures in proteins, metabolites, and lipids, offering a ...
Ultrafiltered Milk Rewrites the Microbial and Flavor Chemistry of Cheese
A new multi-omics study shows that ultrafiltration reshapes microbial metabolism and flavor chemistry in cheese, boosting umami amino acids and ...
Sugar and Rice Flour Reshape the Flavor Chemistry of Low-Salt Shrimp Paste
A metabolomics study shows that adding glucose or glutinous rice flour to low-salt shrimp paste fermentation enhances protein breakdown, suppresses ...
Fungi and Gut Microbes Reshape the Tea Compound EGCG in Surprisingly Different Ways
New metabolomics research shows that the fungi behind dark tea fermentation and rat gut microbiota transform the tea catechin EGCG ...
Why Some Porcini Taste Better Than Others: Chemistry Cracks the Bolete Flavor Code
A new study combines mass spectrometry, infrared spectroscopy, and deep learning to identify the exact taste and aroma compounds that ...
Blood Test Score Predicts Heart Disease Years Ahead—and Improves with Lifestyle Change
A clinically validated metabolic blood score predicts mortality and delays cardiometabolic disease by nearly 14 years per unit, and improves ...
Gut Microbes and Blood Chemistry Reveal Hidden Metabolic Signature of Parkinson’s Disease
A multi-omics study of 67 Parkinson's disease patients and 64 controls reveals microbial-driven lipid and amino acid pathways, with gut-derived ...
Coffee Compound Trigonelline Eases Parkinson’s Symptoms in Mice by Calming Brain Inflammation and Reshaping Gut Microbes
A new preclinical study shows that trigonelline, a coffee-derived alkaloid, reduces alpha-synuclein pathology and neuroinflammation in Parkinson's model mice while ...
Clamworm Compounds Show Promise Against Alcoholic Liver Damage in Mice
Maillard reaction products derived from the marine clamworm Perinereis aibuhitensis protected mice against alcohol-induced liver injury by restoring antioxidant, anti-inflammatory, ...
Fermented Foods May Talk to the Brain: The Science of Psychobiotics Goes Beyond Probiotic Pills
A new review in npj Science of Food argues that fermented foods should be studied as integrated psychobiotic systems in ...
Glutamine Emerges as a Hidden Nitrogen Lifeline for the Leptospirosis Pathogen
Researchers found that the amino acid glutamine, abundant in human plasma, serves as a major nitrogen source for Leptospira interrogans ...
Placenta-on-a-chip reveals how toxic metals cross from mother to fetus
A microfluidic model built from primary human placental cells shows how cadmium undermines placental function at doses that cause no ...
Order Beats Time: AI Cracks Retention Prediction Across Any Chromatography Setup
Researchers have developed a two-step machine-learning method that predicts small-molecule retention times in liquid chromatography for any experimental setup without ...
How Well You Care for Your Brain Shows Up in Your Retina, Massive Study Finds
A UK Biobank study of nearly 29,000 adults links higher brain care scores to thicker retinal layers and a biologically ...
Aging Cells Lose Their Recycling Machinery, Letting Senescent Cells Pile Up
New research in Nature Aging shows that the age-related decline of chaperone-mediated autophagy distorts the senescent cell secretome and disables ...
Scientists Decode the Molecular Secrets Behind Liupao Tea’s Four Signature Aromas
A new flavoromics and molecular docking study identifies the volatile and non-volatile compounds that distinguish the betelnut, stale, ginseng, and ...
Popular RUBY plant reporter shown to disrupt growth and hormone balance
New research shows that the widely used betalain-based RUBY reporter disrupts hormone and amino acid homeostasis in Arabidopsis, impairing growth, ...
Sword Bean Gets Its Full Genetic Blueprint in First Complete Telomere-to-Telomere Genome
Researchers have assembled the first gap-free telomere-to-telomere genome of the sword bean and used multi-omics profiling of developing seeds to ...
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