Tag: major depressive disorder

A retrospective propensity-matched cohort study found taVNS and escitalopram showed no significant difference in core depressive symptoms, with taVNS showing ...

A retrospective chart review of 278 adults hospitalized with serious mental illness found that 64.4 percent had an identified primary ...

A retrospective cross-sectional study of 492 acute-phase depression inpatients reports a U-shaped association between serum hs-CRP levels and current psychiatric ...

A new perspective in Frontiers in Psychiatry argues that comorbid depression and substance use disorder demand individualized, multidisciplinary treatment because ...

A cross-sectional study of 930 Chinese adolescents with major depressive disorder identified three suicide risk subtypes, including a low-disclosure group ...

A randomized controlled trial found that combining repetitive transcranial magnetic stimulation with cognitive load training significantly reduced depressive symptoms and ...

This case report examines the severe psychiatric burden, including depression and OCD, experienced by a young adult living with RYR1-related ...

A new opinion article argues that accelerated transcranial magnetic stimulation for depression should be evaluated as a constrained optimization of ...

A cross-sectional study of 103 drug-naïve first-episode depression patients finds elevated morning serum cortisol that correlates with anxiety, cognitive, retardation, ...

An integrative transcriptomic study has identified an extracellular matrix and perineuronal net-high astrocyte state in major depressive disorder, along with ...

A small exploratory prospective NIRS study in Japan found that patients with mood disorders who later attempted suicide showed elevated ...

A pooled analysis of two trials found consistent zuranolone effects across Japanese patient subgroups, with sleep symptoms contributing most to ...

An analysis of 82 neuroimaging studies found substantial convergence between functional and structural brain-network alterations associated with first-episode major depressive ...

A cross-sectional MRI study found that structural and higher-order functional brain features distinguished 154 adults with major depressive disorder from ...

A network meta-analysis of 77 Chinese trials associated manual acupuncture plus SSRIs with the largest short-term reduction in depression scores, ...

Artificial intelligence is quietly transforming two of the most intimate fields of medicine: neuroscience and psychology. A new editorial published ...

A comprehensive review of drugs approved since 2018 reveals rapid innovation in schizophrenia, bipolar disorder and depression, while anxiety disorders ...

A sweeping integrative review argues that major depressive disorder arises from interacting molecular dysregulation and large-scale brain network dysfunction, while ...

A new mouse study shows that a complex between the sigma-1 receptor and the serotonin 1A receptor disinhibits a key ...

A landmark MRI study of over 1,000 people shows that adolescent and adult depression share some structural brain network disruptions ...