Ancient Chinese Formula Shields the Brain by Rewiring Gut Microbes and Metabolism
A multi-omics study shows that the classical Chinese formula Xijiao Dihuang Decoction protects rats against stroke reperfusion injury by remodeling ...
Tag: lipid metabolism
Yogurt Bacterium Extends Healthy Aging by Reprogramming Fat Metabolism in Worms
A new GeroScience study shows that the yogurt bacterium Streptococcus thermophilus extends healthspan in C. elegans by activating the NHR-49/delta-9 ...
Stroke Reshapes Gut Microbes and Brain Chemistry in Rats, Multi-Omics Study Finds
A multi-omics study in rats reveals that permanent middle cerebral artery occlusion remodels cecal microbiota and drives a lipid-centered inflammatory ...
Scientists Switch Off a Key Mechanosensor in Tendon Cells and Map What Breaks
A conditional knockout study shows that deleting the mechanosensor YAP in stretched tendon cells disrupts a broad lipid-metabolism and immune-linked ...
Plasma Cholesterol and IL-18 Flag Persistent Fatigue in HIV Patients Whose Immunity Never Recovers
A combined metabolomics and cytokine study of HIV immunological non-responders identifies elevated cholesterol and altered IL-18, IP-10, and MIF levels ...
Stem Cell Enzyme PLA2G7 Emerges as a Driver of Age-Related Memory Decline
Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in ...
Blood Lipid Patterns Could Predict Which Breast Cancers Respond to Chemotherapy
A new study finds that dynamic changes in blood lipid levels during chemotherapy can predict with high accuracy which luminal ...
Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts ...
Fat Rewrites the Rules of Liver Cancer Across Every Disease Stage
A new review proposes that lipid metabolism plays fundamentally different roles at each stage of fatty liver disease progression to ...
Silencing a Fat-Making Master Switch Pushes Pancreatic Cancer Cells Toward Self-Destruction
New research links elevated SREBF1 expression to lipid metabolism signatures in pancreatic cancer and shows that silencing the gene triggers ...
When Ducks Stop Laying, Their Livers Pay a Metabolic Price, Study Finds
A multi-omics study of late-laying ducks reveals that when the ovary regresses, the liver accumulates fat, shows inflammation, and undergoes ...
A Fat in Olive Oil Linked to Slower Alzheimer’s Progression in New Study
New research finds that higher blood levels of oleic acid, a monounsaturated fatty acid abundant in olive oil, are associated ...
Hidden Brain Cells Called Oligodendrocytes Emerge as Unexpected Drivers of Parkinson’s Disease
A spatial multi-omics study in Nature Communications identifies disease-associated oligodendrocytes whose interleukin 33–ST2 signaling influences alpha-synuclein burden and motor symptoms ...
Fat-Processing Gene Variants Tied to Lymphoma Risk and Survival
A Chinese genetic association study links inherited variants in lipid metabolism genes to the risk, severity, treatment response, and survival ...
Gut Microbes and Blood Chemistry Reveal Hidden Metabolic Signature of Parkinson’s Disease
A multi-omics study of 67 Parkinson's disease patients and 64 controls reveals microbial-driven lipid and amino acid pathways, with gut-derived ...
Slaughter Weight Shapes Lamb Meat Quality and Fat Metabolism Genes
A new study of Turkish Lalahan lambs shows that slaughter weight has limited effects on most meat quality traits but ...
The Golgi Apparatus Emerges as a Hidden Driver of Alzheimer’s Disease
A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a ...
Blood Levels of Liver Cancer Drug Lenvatinib Predict Who Responds to Treatment
A multi-omics study of 194 liver cancer patients shows that lenvatinib blood concentrations above 26.5 ng/mL predict treatment response, while ...
How Well You Care for Your Brain Shows Up in Your Retina, Massive Study Finds
A UK Biobank study of nearly 29,000 adults links higher brain care scores to thicker retinal layers and a biologically ...
RNA-Binding Protein ADAR2 Throttles Bladder Cancer Spread by Destroying Fat-Making Enzyme Message
A new study shows that the RNA-binding protein ADAR2 suppresses bladder cancer metastasis by destabilizing FASN mRNA and curbing fatty ...
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