Cellular Stress Switch IRE1α Emerges as Next-Generation Target for Type 2 Diabetes
A new review argues that the evolutionarily conserved IRE1α/XBP1 stress-signaling pathway, which governs protein folding, inflammation and insulin action, offers ...
A new review argues that the evolutionarily conserved IRE1α/XBP1 stress-signaling pathway, which governs protein folding, inflammation and insulin action, offers ...
A study of 360 Brown Swiss cows shows that the dry period and early lactation are the most metabolically stressful ...
New research in Aging Cell shows that aging disrupts pancreatic alpha cell function, driving hyperglucagonemia and increasing diabetes risk in ...
A common inherited variant in the DDIT4 3′ UTR controls translation efficiency of the tumor-suppressing stress-response gene, reshaping mTOR signaling, ...
A rat study shows nicotine damages sperm by triggering a maladaptive endoplasmic reticulum stress response driven by oxidative stress, and ...
A Palestinian family case series shows four girls with the same homozygous WFS1 mutation developing strikingly different Wolfram syndrome features, ...
In a groundbreaking study that sheds light on the intricate interplay between immune cells and cancer therapy resistance, researchers have ...
A groundbreaking study conducted by researchers at the Technical University of Munich (TUM) unveils a novel cellular mechanism linking chronic ...
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