How HPV Reshapes the 3D Genome to Lock Cervical Cancer Into Resistant States
A new review argues that host chromatin architecture and three-dimensional genome rewiring, not just HPV oncoproteins, stabilize malignant states and ...
Tag: Cervical cancer
Silencing HPV16 Oncogenes E5 and E6 Emerges as a Promising Route Against Cervical Cancer
A new review in Virology Journal examines how siRNA and CRISPR/Cas gene-silencing technologies could target the HPV16 oncoproteins E5 and ...
Low Oxygen Inside Tumors Fuels Cervical Cancer Growth and Cisplatin Resistance, Study Finds
Researchers at Chongqing Medical University report that hypoxia silences the tumor suppressor CCNDBP1 in cervical cancer, activating a USP11–Nrf2 antioxidant ...
Texas Unveils Five-Year Roadmap to Eliminate Cervical Cancer by 2032
A statewide coalition led by UT MD Anderson has launched the Texas Lone Star Cervical Cancer Elimination Plan 2027-2032, targeting ...
HPV Vaccine Before Pregnancy Tied to Lower Risk of Preterm Birth, Major Complications
A large Swedish study in The BMJ links quadrivalent HPV vaccination before pregnancy with lower odds of preterm birth and ...
Why Women Skip Cancer Screenings: Rural China Study Maps the Full Journey
A two-phase study in rural northwestern China maps multilevel barriers across the breast and cervical cancer screening journey and shows ...
Proteomic Map of Cervical Cancer Reveals Subtypes and a New Drug Target
A large-scale proteomic study of 404 cervical cancer samples has revealed three molecular subtypes of squamous cell carcinoma with distinct ...
Weekly Scans Reveal Dramatic Uterine Shrinkage During Cancer Treatment After Pregnancy
A small Chinese study using weekly cone beam CT found that the uterus shrank by over 52 percent during chemoradiotherapy ...
Adding Immunotherapy to Chemo and Bevacizumab Extends Survival in Recurrent Cervical Cancer
A retrospective Chinese study finds that adding the PD-1 inhibitor tislelizumab to paclitaxel-carboplatin chemotherapy and bevacizumab significantly improves response rates, ...
Unlocking Treatment-Resistant Cervical Cancers Through Proteogenomics
The relentless pursuit of better therapeutic strategies for treatment-resistant subtypes in locally advanced cervical cancers has garnered significant attention within ...
CLC3 Boosts Lysosomal Function, Drives Cisplatin Resistance
In a groundbreaking study set to reshape the understanding of chemotherapy resistance mechanisms, researchers have unveiled the pivotal role of ...
Combining Chemotherapy with Radiation Leads to Greater Short-Term Quality of Life Decline in Cervical Cancer Patients
A groundbreaking multi-institutional study spearheaded by UCLA Health Jonsson Comprehensive Cancer Center investigators has spearheaded new understanding in the treatment ...
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