Tag: antibody-drug conjugates

A mechanistic model from Mass General Brigham and the University of Cyprus shows how normalizing the tumor microenvironment, without over-tightening ...

A Brazilian study found that an AI model's measure of HER2 staining heterogeneity within breast cancer samples predicts where pathologists ...

A Nature Reviews Clinical Oncology Review proposes a modular biomarker framework that moves ADC patient selection beyond semi-quantitative immunohistochemistry by ...

A new Nature Reviews Clinical Oncology review charts how HER2-targeted therapies, led by trastuzumab deruxtecan, are driving a shift from ...

A new review argues that antibody–drug conjugates act as immune modulators through immunogenic cell death, Fc-mediated effector functions and tumour ...

A new review in Annals of Hematology details how molecular profiling and a growing arsenal of targeted and immune-based therapies ...

The latest volume of SLAS Discovery showcases how artificial intelligence, deep learning and data-mining strategies are accelerating drug discovery across ...

A sweeping new review maps how the epithelial guardian protein MUC1, and especially its MUC1-C signaling subunit, is hijacked by ...

In recent advances presented at the Advanced Breast Cancer Eighth International Consensus Conference (ABC8) held in Lisbon, Portugal, experts have ...

Recent studies have highlighted the complexities and challenges in treating germ cell tumors, particularly those that exhibit resistance to standard ...