Fruit flies evolved distinct genetic routes to establish heads and tails
An embryo’s first great decision is directional: which end will become the head, and which will become the tail? In many animals, this body-axis blueprint...
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MBNL Loss Drives Stem Cell Fusion and Immature Myonuclei in DM1
Myotonic dystrophy type 1, or DM1, has long been recognized as a disease of defective RNA processing, but new research suggests that its damage begins...
Prime Editing Precisely Corrects GJB2 c.235delC Mutation in Laboratory Cells
Hereditary hearing loss may be one step closer to genetic correction after researchers used prime editing to repair a common mutation in the GJB2 gene...
How Tumors Rewire Dendritic Cell–T Cell Communication, Revealing New Therapeutic Opportunities
Dendritic cells and T cells are often described as the immune system’s intelligence network: dendritic cells detect danger and present molecular evidence, while T cells...
AI Designs Functional Bacteriophages Entirely From Scratch
Researchers have used artificial intelligence to design complete bacteriophage genomes from scratch, then synthesized and tested the resulting viruses against bacteria that had evolved resistance...
Genetic testing reshapes hereditary cancer outcomes across a family over 20 years
Marcos Vinícius Sampaio Vieira was 35 when a routine medical visit uncovered three thyroid nodules, including one measuring four centimeters. His hormone levels were normal,...
Siberia’s Rising Methane Threat Could Erase 20% of Global Cuts by 2050
The Arctic is warming faster than the global average, and Siberia is emerging as one of the most important—and least understood—fronts in the climate system....
Study Finds Accessible Education Helps Urban Growers Adopt Pollinator-Friendly Practices
Urban farms may be surrounded by biodiversity, yet the decision to protect and support pollinators appears to depend less on what growers plant—or who those...
Penn Nursing Professors Examine How Trauma, Stress, and Violence Affect Health
PHILADELPHIA, August 6, 2026 — Chronic stress, traumatic experiences, and exposure to violence can alter the body’s biological systems long after an immediate threat has...
New conservation project protects rare wildlife in orchards
Scientists from Aberystwyth University are joining a major conservation project aimed at protecting some of Britain’s rarest orchard species, combining cutting-edge molecular ecology with habitat...
PPARα Activation Overcomes Fibroinflammatory Anti-PD-1 Resistance in Liver Cancer via GSDME Pyroptosis
Hepatocellular carcinoma, the most common primary cancer of the liver, has become a major testing ground for immunotherapy. Drugs that block the PD-1 immune checkpoint...
New strategy boosts TOPCon solar cell power conversion efficiency
Solar scientists have unveiled a new metallization strategy that has pushed tunnel oxide passivated contact (TOPCon) solar cells to a certified power conversion efficiency of...
Alert-Based Patient-Reported Outcome Monitoring in Metastatic Breast Cancer
A randomized clinical trial in breast cancer care has found that digital monitoring of patient-reported outcomes was associated with clinically meaningful reductions in fatigue and...
Two Decades of Blazar Observations Reveal More Mysteries Than Answers
A blazar located about 1.5 billion light-years away has challenged one of astronomy’s most widely used explanations for how these extreme cosmic objects shine. After...
Why Longevity Research Must Prioritize Women
Women may hold one of nature’s most important clues to the biology of aging, according to a new perspective published in Cell. The paper introduces...