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		<title>Apelin Hormone Fails to Boost Urine Output in First Human Trial of Induced Hyponatremia</title>
		<link>https://bioengineer.org/apelin-hormone-fails-to-boost-urine-output-in-first-human-trial-of-induced-hyponatremia/</link>
		
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		<pubDate>Sat, 17 Oct 2026 17:39:16 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Apelin]]></category>
		<category><![CDATA[apelin-13]]></category>
		<category><![CDATA[clinical trial]]></category>
		<category><![CDATA[Desmopressin]]></category>
		<category><![CDATA[Endocrinology]]></category>
		<category><![CDATA[Healthy]]></category>
		<category><![CDATA[hyponatremia]]></category>
		<category><![CDATA[Intravenous]]></category>
		<category><![CDATA[SIADH]]></category>
		<category><![CDATA[vasopressin]]></category>
		<category><![CDATA[Volunteers]]></category>
		<category><![CDATA[water balance]]></category>
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					<description><![CDATA[A double-blind crossover trial in 15 healthy volunteers found that intravenous [Pyr¹]apelin-13, at both high and low doses, did not increase urine output compared with placebo in an artificially induced syndrome of inappropriate antidiuresis, tempering hopes raised by rodent studies.]]></description>
		
		
		
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