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		<title>Bacterial Toxin Hijacks Mitochondria to Trigger Fatal Cell Death in Bovine Mastitis</title>
		<link>https://bioengineer.org/bacterial-toxin-hijacks-mitochondria-to-trigger-fatal-cell-death-in-bovine-mastitis/</link>
		
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		<pubDate>Fri, 09 Oct 2026 04:29:34 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[Health]]></category>
		<category><![CDATA[autophagy]]></category>
		<category><![CDATA[cGAS-STING]]></category>
		<category><![CDATA[ferroptosis]]></category>
		<category><![CDATA[GPX4]]></category>
		<category><![CDATA[mastitis]]></category>
		<category><![CDATA[Mic60]]></category>
		<category><![CDATA[MICOS]]></category>
		<category><![CDATA[mitochondrial cristae]]></category>
		<category><![CDATA[mitochondrial DNA]]></category>
		<category><![CDATA[sphingomyelin phosphodiesterase]]></category>
		<category><![CDATA[Staphylococcus aureus]]></category>
		<category><![CDATA[virulence factor]]></category>
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					<description><![CDATA[New research reveals that the Staphylococcus aureus virulence factor Sph disrupts mitochondrial cristae through Mic60, releasing mtDNA that activates the cGAS-STING pathway and drives autophagic degradation of GPX4, promoting ferroptosis in mastitis.]]></description>
		
		
		
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		<title>Zinc-Dependent Enzyme From Leptospira Revealed as Collagen-Degrading Virulence Candidate</title>
		<link>https://bioengineer.org/zinc-dependent-enzyme-from-leptospira-revealed-as-collagen-degrading-virulence-candidate/</link>
		
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		<pubDate>Fri, 09 Oct 2026 03:58:22 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[cell-free protein synthesis]]></category>
		<category><![CDATA[collagenolysis]]></category>
		<category><![CDATA[extracellular matrix]]></category>
		<category><![CDATA[Leptospira interrogans]]></category>
		<category><![CDATA[leptospirosis]]></category>
		<category><![CDATA[M23 metallopeptidase]]></category>
		<category><![CDATA[MALDI-TOF]]></category>
		<category><![CDATA[metalloprotease]]></category>
		<category><![CDATA[signal peptide]]></category>
		<category><![CDATA[Type I collagen]]></category>
		<category><![CDATA[virulence factor]]></category>
		<category><![CDATA[zinc-dependent enzyme]]></category>
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					<description><![CDATA[Researchers have characterised for the first time the zinc-dependent metalloprotease LIC11568 from Leptospira interrogans, showing that the enzyme degrades Type I collagen in vitro and may contribute to the tissue-invasive ability of the leptospirosis pathogen.]]></description>
		
		
		
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