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	<title>upper motor neuron &#8211; BIOENGINEER.ORG</title>
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		<title>ALS&#8217;s &#8216;Lateral Sclerosis&#8217; Revealed as a Dying-Back Degeneration of Upper Motor Neuron Axons</title>
		<link>https://bioengineer.org/alss-lateral-sclerosis-revealed-as-a-dying-back-degeneration-of-upper-motor-neuron-axons/</link>
		
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		<pubDate>Fri, 09 Oct 2026 13:30:25 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[amyotrophic lateral sclerosis]]></category>
		<category><![CDATA[axonal degeneration]]></category>
		<category><![CDATA[corticospinal tract]]></category>
		<category><![CDATA[dying back axonopathy]]></category>
		<category><![CDATA[foamy microglia]]></category>
		<category><![CDATA[lateral sclerosis]]></category>
		<category><![CDATA[motor neuron disease]]></category>
		<category><![CDATA[myelin loss]]></category>
		<category><![CDATA[Neuroinflammation]]></category>
		<category><![CDATA[spinal cord pathology]]></category>
		<category><![CDATA[TDP-43]]></category>
		<category><![CDATA[upper motor neuron]]></category>
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					<description><![CDATA[A clinical-neuropathological study shows that the lateral sclerosis of ALS reflects a length-dependent dying-back degeneration of upper motor neuron axons, accompanied by myelin loss, foamy microglia, and elevated axonal TDP-43.]]></description>
		
		
		
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