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	<title>UBR5 &#8211; BIOENGINEER.ORG</title>
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		<title>CRISPR Screen Maps the Hidden Control Network of the Body&#8217;s Pollution-Sensing Receptor</title>
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		<pubDate>Fri, 09 Oct 2026 09:51:09 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[aryl hydrocarbon receptor]]></category>
		<category><![CDATA[CRISPR screening]]></category>
		<category><![CDATA[E3 ubiquitin ligase]]></category>
		<category><![CDATA[Gene regulation]]></category>
		<category><![CDATA[Gut microbiome]]></category>
		<category><![CDATA[hepatocytes]]></category>
		<category><![CDATA[host-microbe interactions]]></category>
		<category><![CDATA[inflammatory disease]]></category>
		<category><![CDATA[microbial metabolites]]></category>
		<category><![CDATA[transcription factor]]></category>
		<category><![CDATA[UBR5]]></category>
		<category><![CDATA[xenobiotic detoxification]]></category>
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					<description><![CDATA[A genome-scale CRISPR screen in human hepatocytes has revealed an extensive network of regulators governing the aryl hydrocarbon receptor, including the E3 ubiquitin ligase UBR5, with implications for treating metabolic and inflammatory disease.]]></description>
		
		
		
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